Children With Whooping Cough Capsule Adjust The Experimental Study Of Bronchial Asthma, Immune Balance

Purpose: Bronchial Asthma(abbreviation asthma) is a kind of commonrespiratory system disease. It is a chronic airway allergicreaction inflammation which cause by the Eosinophil (EOS),the adipose cell, the T-lymphocyte cell and so on .And asthma bring out Airway hyperreactivity (AHR) to patient,thus causepatient's airway remodeling.This topic through the immunology experimental technique, examines the young child to wheeze the coughing and gasping capsule adjustment bronchial tube asthma immunologic balance functionMethod: The guinea pig divides into 7 groups stochastically, each group of 8: normal control group, the asthmatic model group, Aminophylline group, Kechuanling Keli dose,Xiaokechuan Jiaonang( Capsule for infantile cough and asthma ) large dose group, medium dose group and small dose group, Uses the ovalbumin (OVA) atomization inspiration sensitization stimulation law duplication asthma model. Each group gives the corresponding medicine separately. Records each group of guinea pigs to direct to breathe heavily the incubation period, the pulmonary alveolus syringe fluid (BALF) the acidophilia granular cell (EOS) quantity, The observation lung bronchial tube organization shape, examines in the blood serum IFN-γ, the IL-4 content. Compared with the above examination project in each group of guinea pigs whether to have the difference.Result: Xiaoer Xiaokechuan Jiaonang( Capsule for infantile cough and asthma ) enhances asthma model obviously the breath function, improves the asthma general condition. Can control asthma model obviously the gas channel inflammation, reduces the EOS quantity, adjusts between the Thl/Th2 cell to be balanced.Conclusion: Xiaoer Xiaokechuan Jiaonang( Capsule for infantile cough and asthma ) has the adjustment bronchial tube asthma immunologic balance function.