Vaccination Coverage Of Children In Tianjin And Evaluation On Methods Of Sampling Investigation

Objective:To understand the various vaccination rates in children in Tianjin, the reason of no vaccination and appointment methods for next vaccination. to evaluate three sampling investigation methods, in order to provide scientific evidence for choice of the best sampling method and the development of featuring vaccination management strategies in Tianjin.Methods:The building certificate rate, building card rate, consistent rate of certificate and card and the various vaccination rates in children were investigated in Tianjin by three sampling methods, including sampling of probability proportional to size (PPS), systematic sampling and stratified cluster sampling. Imformation was collectedd by means of a self-made questionnaire. IgG antibodies to diphtheria were measured by ELISA. Epidata 3.1 software was used to establish database and collating information, SPSS13.0 software was used for statistical analysis. Proportions and rates among differenct groups were compared using Chi square tests. Logistic regression analyses were used to estimate the odds ratios (ORs) and 95% confidence interval (CIs) of vaccination in relation to appointment methods for next vaccination.Results:1 The building certificate rate and building card rate reached more than 90% in children in Tianjin,The consistent rate of certificate and card obtained by PPS, systematic sampling and stratified cluster sampling were 93.75%,81.67% and 71.11% respectively. The vaccination coverage of BCG, OPV, DPT, MV, HepB reached more than 90%.2 The building certificate rate, building card rate and vaccination coverages of BCG, OPV, DPT, MV, HepB in local children aged 1 to 2 years were higher than in migrant worker children, which obtained by PPS. The difference had statistical significance (P<0.05). The building certificate rate, the consistent rate of certificate and card and vaccination coverages of OPV, MV, HepB in urban children were higher than in rural children. The difference had statistical significance (P<0.05).3 The boosted vaccination coverages of OPV, DPT, MMR, Men AC and JEV were from 48.86% to 86.16% investigated by stratified cluster sampling, which were lower than routine vaccination coverages. The difference had statistical significance (P<0.05).4 Among the children with disqualification of vaccination,35.08% were for over time vaccination,25.65% for early time vaccination,11.52% for interval unconformity and 27.75% for no vaccination respectively. "Being ill" was the main reason for no vaccination.5 The results of logistic regression analyses showed that appointment for next vaccination was associated with high vaccination coverage.6 There were no statistical significant difference among building certificate rates obtained by PPS, systematic sampling and stratified cluster sampling (P>0.05).The building card rate and consistent rate of certificate and card obtained by PPS were higher than those by stratified cluster sampling (P<0.05). The consistent rate of vaccination coverages obtained by PPS and systematic sampling was high (87.5%), while that obtained by PPS and stratified cluster sampling was low (25%).7 There was no statistical significant difference between the estimated and investigated vaccination coverages (P>0.05).Conclusion:The building card rate, the buliding certifieate rate, and vaccination coverages of BCG, OPV, DPT, MV, HepB in Tianjin reach more than 90%, which reach national standard of China. The consistent rate of certificate and card is lower than 95%, and lower in rural and migrant worker children. The boosted vaccination coverages of OPV, DPT, MMR, Men AC and JEV were lower than routine vaccination coverages. The disqualification of vaccination include over time vaccination, early time vaccination, interval unconformity and no vaccination. "Being ill" was the main reason for no vaccination. The consistent rate of vaccination coverages obtained by PPS and systematic sampling was high, and vaccination coverages obtained by stratified cluster sampling were lower than those obtained by PPS and systematic sampling.