The Influence Anxiety Syndrome To Female Patients With Acute Coronary Syndrome

Background and ObjectivesAlong with the progress of society and technology,simple medical model will be passed,the comprehended medical model witch is society psychology and biology will come.The realization of healthy and disease has left the higher level.People study the coronary artery disease frome mental health social psychology behavioral medicine psyche nerve immunity rehabilitation,except the good future.The main clinical feature of anxiety which often occurs after other organic disease is extensive and persistensive anxiety or recurrent attacks panic. According to statistics, the incidence of psychological stress status in patients with coronary artery disease is about 45%, the low grade is 30%, the fanty is 15%-23%.Study has reported the incidence of psychological stress status in patients with acute coronary syndrome is higher.Study have certificated that the vascular endothelium injuries Inflammatory reaction and stabilize of atherosclerotic plaque are linked to the prognosis of acute coronary syndrome,IL-6 and CRP are main sensitive but non-specific inflammatory factor,the level of inflammatory factor is linked to the stabilize of atherosclerotic plaque.To investigate the relationshop between anxiety syndrome and inflammatory factor, in order to provide doctors with experimental basis for their potency evaluation.Materials and Methods Patients:100 hospitalized cases diagnosed as acute coronary syndrome having received coronary arteriongraphy from December,2009 to February,2011 were selected. Exclusion criteria:consciousness disorders, those who have liver or renal disfunction,those who have tumor or disease of immune system,those who have rheumatism,those who have disease of other inflammation or have cerebrovascular disease.Methods:All patients were divided into 2 groups, one group with anxiety syndrome and the other group without.Outcome Measures:The serum levels of IL-6 and CRP were determined in patient with acute coronary syndrome, cardiovascular events are observed in every group.Statistical analysis:We used the SPSS 13.0 version to carry on statistics processing analysis, the different examination uses the T-test or the card side or Spearman examination, P<0.05 indicates that the difference has statistics significance.ResultsThe difference between the two groups has not statistic significance in age, vocational education, blood pressure, blood fat,blood glucose,smoking and so on.The difference between the two groups has not statistic significance in coronary artery pathological changes.The serum levels of IL-6 and CRP in the group with anxiety is 101.1±22.3 ng/L and14.90±4.86 g/L, The serum levels of IL-6 and CRP in the other group is 71.2±23.5 ng/L and 6.76±4.02 g/L. The difference between the two groups has statistic significance (P<0.05)。In the group with anxiety the levels of beke are along with the serum levels of IL-6(r=0.881) and CRP(r=0.822).The rate of cardiovascular events in the group with anxiety is 64.71%, the rate of cardiovascular events in the other group is28.57%, The difference between the two groups has statistic significance (P<0.01)。ConclusionsThe serum levels of IL-6 and CRP in group with anxiety syndrome is higher, in the group with anxiety the levels of beke are along with the serum levels of IL-6) and CRP. The cardiovascular events in group with anxiety syndrome is higher. Anxiety syndrome may affect the prognosis of acute coronary syndrome through the serum levels of IL-6 and CRP.