A Clinical Report Of 27 Cases Of Emergency Liver Transplantation

OBJECTIVE:To summarize the experience of emergency liver transplantation for severe liver disease.METHODS:The clinic data of 27 cases of recipients who underwent emergency liver transplantation in our department, from January 2005 to October 2010, were retrospectively analyzed.RESULTS:Among the 27 patients,20 discharged after surgery, while 7 died during hospitalization. The hospital mortality of all recipients was 25.9%,6 months and 1 year survival rates were 74.1% and 70.4% respectively.4 cases of 5 ABO-incompatible liver transplantation recovered except that 1 patient died of MODS. All the 4 patients who were treated with artificial liver support system before operation went well.1 case of living donor liver transplantation recovered well, and has been alive for 27 months. Higher MELD score and serum creatinine level were found in the dead group during hospitalization, as compared to those in survival group (0.05<P<0.10); The gender, age, total bilirubin, PT, and ALB showed no significant difference between the survival and death group (P> 0.10); The survival rates also showed no significance between ABO-matched and ABO-incompatible group (P> 0.10).CONCLUSIONS:1.For critically ill patients with liver disease, we should choose the appropriate recipients for emergency liver transplantation, to avoid the waste of valuable medical resources.2.Perioperative management should be strengthened to improve the success rate of surgery and recipient survival rates.3.ABO-incompatible liver transplantation and living donor liver transplantation in critically ill patients may shorten the waiting time for donor and can achieve good effect, it is worth a wider range of research and application.