Establishment Of Screening Model Based On Study Of Clinical Predicting Marker In Differential Diagnosisof Benign And Malignant Ascites

Objective Clinical routine examination of a number of benign and malignant differential diagnosis of ascites.Method Retrospective analysis of our hospital from 2003 to December 2010 patients with ascites admitted to hospital and Baotou Central Hospital from 2007 to December 2009 hospitalized patients with ascites were some 212 cases, 111 patients were male, 101 cases of female patients. Results 212 patients with ascites diagnosed cases, 135 cases of benign ascites, the main cause of cirrhosis (43%), unknown causes (30%), tuberculous peritonitis (17.8%), COPD (2.2%), chronic renal failure (1.5%) , purpura (1.5%), other causes (3.5%). 77 cases of malignant ascites, the cause is mainly unknown reasons (27.3%), ovarian cancer (24.7%), liver (15.6%), stomach (11.7%), peritoneal metastatic carcinoma (7.8%), other tumors (13%). Between the two groups have a direct bilirubin, alanine aminotransferase, glutamyltransferase GGT, alkaline phosphatase, CEA, CA50, appearance, Rivalta test, specific gravity, cytology was statistically significant difference. Between the two groups of hemoglobin, red blood cells, white blood cells, platelets, total bilirubin, alanine aminotransferase, aspartate aminotransferase, serum total protein, Na, K, Cl, Ca, AFP, CA199, CA125, white blood cell count, total protein, white protein, glucose, lactate dehydrogenase, chlorine difference was not statistically significant. Conclusions The top three etiological diagnosis of malignant ascites are cirrhosis, unexplained ascites, tuberculous peritonitis; diagnosis of malignant ascites top three causes were unexplained ascites, ovarian cancer, liver cancer. The direct bilirubin, alanine aminotransferase, glutamyltransferase GGT, alkaline phosphatase, CEA, CA50, appearance, Rivalta test, the proportion of benign and malignant ascites cytology differential diagnosis of clinical significance.