Evaluate Postorative Clinical Efficacy Of PCI On Coronary Heart Disease By Pulse Wave Velocity And Plasma Brain Natriuetic Peptide

ObjectiveThe purpose is assessment of the clinical efficacy and prognostic factors of percutaneous coronary intervention (PCI).in patients with coronary artery disease according to ankle-brachial pulse wave velocity (baPWV) and plasma brain natriuretic peptide (BNP).Methods139 patients with CHD from percutaneous coronary intervention and complete data of department of Cardiology of our hospital,who was selected and received conventional medicine therapy, 79 patients were male and female 60 cases, aged 44 ~ 86 years (mean age 65.4±10.5) years, tomeasured baPWV, BNP, and height and weight in preoperative, and routine tesed of blood biochemical parameters, and recorded the age, sex, history of hypertension, diabetes, history, family history of coronary heart disease, smoking history and alcohol history. The patients were grouped respectively according to BNP and baPWV The patients were divided into three groups according to baPWV value, baPWV <10m / s group (n = 64), 15m / s> baPWV≥10m / s group (n = 43), and baPWV≥15m / s group (n = 32). Postoperative adverse cardiac events follow-up after 30 days and 1 year (cardiac death, recurrent myocardial infarction, recurrent angina, re-admission of the composite end point and secondary heart failure ) were investigated. Of which 139 patients according to measurement of plasma brain natriuretic peptide (BNP) were divided into four groups: BNP≤100 ng / L group (n = 57); 100ng / L <BNP≤500 ng / L group (n = 36); 500ng / L <BNP≤1000 ng/L组(n=25)和BNP> 1000 ng / L group (n = 21). Postoperative adverse cardiac events follow-up after 30 days and 1 year (cardiac death, recurrent myocardial infarction, recurrent angina, re-admission of the composite end point and secondary heart failure ) were investigated. Postoperative PCI factors from patients with coronary heart disease was on the statistical analysis to to evaluate the long-term and short-term postoperative clinical efficacy and influencing factors. SPSSll.5 statistical software were used for analysis, P <0.05 was a significant statistical difference.ResultsComparison from baseline clinical datas of all patients had no statistical difference, according to baPWV value group, The incidence of cardiovascular adverse events from the patients of postoperative PCI within 30 days were 0,2.2% and 0,3 and no significant difference between groups .The patients were follow-up at 1 year of postoperative PCI, the incidence of cardiovascular events were 9.5%, 17.1% and 32.1%, The incidence of the highest rates of cardiovascular adverse events was which the patiens were from baPWV≥15 m / s group .and patients of baPWV <10 m / s group differences had a statistically significant (P <0.05). The incidence of mortality and MACE was significantly increasing trend, with elevated plasma BNP levels according to BNP values.The mortality in each group were 0%, 1 ? 4%, 7 ? 7%, 48 ? 3% at 3 months .MACE rates were 7 ? 9%, 17 ? 1%, 57 ? 7%, 79 ? 3%. When the risk factors for coronary heart disease baPWV, BNP in the same models to predict the prognosis and efficacy of patients with PCI, The elevation of baPWV, BNP levels at all the factors independently predict long-term and short-term mortality and MACE incidence. Mortality and MACE incidence of postoperative PCI was effected bidence of postoperative PCI was effected by hypertension,diabetes,total cholesterol,LDL,smoking family history,pulse pressure and age and other factors.ConclusionsBNP and baPWV can be a good line of PCI in patients with coronary heart disease risk stratification after treatment, respectively, and can predict Mortality and MACE incidence of the short-term, long-term. BNP and baPWV was a simple, easy clinical indicators used to assess treatment the prognosis. The BNP and baPWV as prognostic indicators for monitoring will help reduce the mortality of patients after PCI and the incidence of MACE. PCI in patients with coronary heart disease after treatment, mortality and the incidence of adverse cardiac events was by hypertension, diabetes, total cholesterol, LDL, smoking, family history, pulse pressure and age and other factors. With the high-density lipoprotein cholesterol was negatively correlated (P <0.05)).