The Clinical Study Of CT Image Analysis On The Relationship Of Osahs Lesions And Upper Airway Lacunar Volume

[Objective](1) Compare the OSAHS group with normal control group under the upper airway nasal cavity,nasopharynx, retro palatal, epiglottal volume, multi-lacunar volume and the pharynx total volume measured values in a quiet breathing of the awake state. Then determine which metrical index with OSAHS diagnosis and obstructed location has statistical significance.(2) Analysis the volume of each lacunar total volume percentage difference of the OSAHS group and the upper airway in the nomal group,and then discuss the role of lacunar volume in the pathogenesis of OSAHS.(3) Compare lacunar volume differences between OSAHS mild to moderate group with severe group and judge the change of the volume of each lacunar disease severity in patients with OSAHS(4) Analysis the correlation of nasal cavity, nasopharynx, retro palatal, retro glossal, epiglottal volume, total volume of the upper airway and lacunar volume accounted for a percentage of the total upper airway volume in the OSAHS groups and their apnea-hypopnea index (AH1), to make clear the position of various cavities in the pathogenesis of OSAHS.[Method](1) Twenty-five patients diagnosised for OSAHS by the Polysomnography instrument monitoring, nineteen normal adult with no snoring history, under the quiet breathing of the awake state,64-slice spiral CT continuous scanning respectively. The obtained image will be demolition for thin, thickness of1.Omm, interval0.7mm. Three-dimensional reconstruction of the entire upper airway is made by multi-planar reconstruction and volume rendering of the MMWP software workstation.Measure nasal cavity, nasopharynx, retro palatal, retro glossal, epiglottis, the posterior region of partial volume, multiple lacunar volume and the pharynx total volume, compare the difference of the measured parameters between the two groups.(2) Calculate the OSAHS group and normal group their respective percentages in upper airway volume about nasal cavity, nasopharyngeal, retro palatal, retro glossal, epiglottal, multiple lacunar volume,then compare the difference of each cavity volume percentage between the two groups.(3) Divide the OSAHS into mide and moderate group and severe group,compare the each part differences of nasal cavity, nasopharyngeal, retro palatal, retro glossal, epiglottal between the two groups.(4) Recorde the AHI values of twenty-five OSAHS patients and analysis the correlation of AHI and nasal cavity, nasopharyngeal, retro palatal, retro glossal, epiglottal each valume, upper airway total volume and each lacunar volume accounted upper airway volume percentage about OSAHS patients.[Results](1) In the awake state and calm breathing, the OSAHS group and the nomal group have statistical significance in retro palatal volume,nasal cavity and retro palatal,retro palatal and retro glossal volume, retro palatal and retro glossal and epiglottal volume (P<0.05),but the difference of nasal cavity,nasopharynx,retro glossal,epiglottis, nasal cavity and nasopharynx, nasal cavity and retro palatal, nasal cavity and retro glossal, retro glossal and epiglottis volume, the total upper airway volume was not statistically significant(P>0.05).(2) The OSAHS group and the nomal group in nasal cavity,nasal cavity and nasopharynx, nasal cavity and retro glossal, retro palatal,retro glossal, nasophary-nx and retro palatal,retro palatal and retro glossal and epiglottal volume accounted for upper airway total volume percentage has statistical significance difference (p<0.05), the difference of nasopharynx, retro glossal, epiglottis, nasal cavity and retro palatal, retro glossal and epiglottal volume accounted for upper airway total volume percentage was not statistically significant(P>0.05).(3) The difference of lacunar volume between the OSAHS patients with mild to moderate group and severe group have no statistical significance(P>0.05).(4) In the awake quiet breathing phase,the nasal cavity, nasopharynx, retro palatal, retro glossal, epiglottal volume and their each volume percentage in upper airway volume about OSAHS patients don't have significantly correlation with the severity of AHI.(5) The total upper airway volume of OSAHS have not significantly associated with AHI.[Conclusion](1)64-slice spiral CT with three-dimensional reconstruction of upper airway lacunar volume measurement can better judge OSAHS patient-specific stenotic plane. The results prove that most OSAHS patients in the waking state and calm breath exist different degree of all the cavity anatomy narrow,it may be caused by many lacunar, one of the most common and main obstructing plane is retro palatal.(2) The effect of nasal factors in the pathogenesis of OSAHS is not obvious, it may be not an independent risk factor.But the effect of retro glossal in the pathogenesis of OSAHS is important.(3) In the awake quiet breathing phase,the nasal cavity, nasopharynx, retro palatal, retro glossal, epiglottal volume and their each volume percentage in upper airway volume,the total upper airway volume about OSAHS patients have no signify-cantly correlation with the severity of AHI.