Research On The Hydrodynamics Change Of Cerebrospinal Fluid Flow At The Craniocervical Junction In Adolescent Idiopathic Scoliosis

Objective:Study of adolescent idiopathic scoliosis patients with cranio cervical junction region of cerebrospinal fluid dynamics characteristics, and to explore its relationship with adolescent idiopathic scoliosis patients with craniocervical junction anatomy structure change and adolescent idiopathic scoliosis pathogenesis relationship.Methods: Application of routine MRI and MR phase contrast cine magnetic resonance imaging (Phase Contrast cine Magnetic Resonance Image, PC-cine MRI) on32patients with adolescent idiopathic scoliosis patients and30cases of normal people were compared with the same age, and axial foramen magnum level determination of Argus cerebrospinal fluid flow; flow analysis software, measurement and calculation parameters including cerebrospinal fluid head end to end phase duration (DF). end to end phase duration (UF), calculated respectively in a CSF cycle time of the percentage of DF%and UF%, DF flow starting time (DS) during a CSF cycle time centile position DS%, latency/a cerebrospinal fluid circulation time (SP%), cerebrospinal fluid flow down the maximum velocity (VDmax), the upward flow of the maximum velocity (VUmax), rendering the maximum velocity/time curve. And the measurement of conventional median sagittal cerebellar tonsil relative to the foramen magnum line position and foramen magnum anteroposterior diameter, the total width of cerebrospinal fluid clearance and foramen magnum anteroposterior diameter ratio. Taking SPSS11.0software for statistical analysis, measurement data for comparison between groups in group t test, within group comparisons with paired t test, correlation analysis using simple linear regression analysis and multiple linear regression; select P<0.05as there are statistically significant differences in P<0.01, there was significant difference.Results:Scoliosis group compared with the control group: DS%and SP% increased, DF%decreased, the differences were statistically significant (P<0.01); UF%, VDmax and VUmax were not statistically significant; the foramen magnum anteroposterior diameter increases, cerebrospinal fluid cerebrospinal fluid clearance gap total width decreases, the total width and foramen magnum anteroposterior diameter ratio decreases, the difference between groups was statistically significant significance of (P<0.05). Scoliosis group in the56.3%position of the cerebellar tonsils below the foramen magnum. The results of correlation analysis showed that: AIS in patients with foramen magnum cerebrospinal fluid flow and abnormal position of the cerebellar tonsils below the foramen magnum line, DS%and SP%values and cerebellar tonsil relative to the foramen magnum line position value is negatively related to h (r=-0.943, P=0.000; r=-0.893, P=0.000), DF%of value and brain tonsil relative to the foramen magnum. Location of the H values were positively correlated (r=0.912,P=0.000). Scoliosis group BO line length and cerebellar tonsil relative BO line position (H) there is correlation, negative correlation (r=-0.937). Cerebrospinal fluid clearance width and foramen magnum anteroposterior diameter ratio decreases with the position of the cerebellar tonsils below the foramen magnum line of relevance, positively related (r=0.765).Conclusions:(1) in adolescent idiopathic scoliosis patients exist the craniocervical junction abnormal cerebrospinal fluid dynamics;(2) the foramen magnum cerebellar tonsillar low is a cause of adolescent idiopathic scoliosis patients with craniocervical junction circulation of cerebrospinal fluid obstruction is one of the reasons;(3) in adolescent idiopathic scoliosis patients before and after the presence of foramen magnum size increases, consider and adaptation to altered cerebrospinal fluid dynamics;(4) in adolescent idiopathic scoliosis patients with craniocervical junction circulation of cerebrospinal fluid abnormalities may be the cause of.