Used In Explosive Detection Nanometer Molecular Imprinting Biochemical Sensor Design

With the development and progress of society, the role of explosives in the national production, military security and other areas is increasingly remarkable. At the same time, explosives are also used by the outlaws for creating social chaos, which makes great threat to the people’s lives and property safety. Therefore, taking effective measures for accurate detection and standard management the explosives is the guarantee of social stability and harmony, which also has far-reaching impact of safeguarding national security, maintaining social stability, and enhancing the ability of our security. Based on the specific recognition of molecularly imprinted polymer and the quality sensitive response of piezoelectric quartz crystal, a kind of explosive detection method based on Molecular Imprinting Technology and piezoelectric response is studied in this paper.The comprehensive overview of the explosives detection methods and the advantages and disadvantages of the various trace detection technology were given in the paper, and the preparation methods of various molecular imprinted polymer as well as the principle of ihe-biomimetic sensor based on various conversion modes were also described. After careful analysis, nano-molecular imprinting piezoelectric sensor was made by using Molecularly Imprinted Polymers (MIP) as the recognition element and the piezoelectric quartz crystal as conversion element. Nano-MIP of explosive molecules of TNT, RDX and NH4NO3are prepared respectively by the surface molecular imprinting method with the nanometer silicon ball as a substrate which was prepared in alkaline environment. The spin-coating method was adopted for modifying piezoelectric crystal, and the adsorption and specificity of these kinds of MIP were verified under isothermal conditions. Through the comparison of the signal of detection circuit and reference circuit, the effect of interference on the difference frequency signal was eliminated as far as possible, which can accurately determine the presence of explosives in the analyte.The MIP adsorption experiment results show that the prepared MIPs have a better combination with their corresponding explosive template molecules. And also the sensor has good reusability. The sensor is small, portable and low cost, which is expected to be used in airports, train stations and other security departments.