Studies On The Coupling Of Nitroarenes With Arylboronic Acids Catalyzed By Cyclopalladated Ferrocenyliminne

A novel palladium-catalyzed protocol for the synthesis of diaryl ethers derivatives has been developed in the thesis. In the presence of2,2’-bipyridine-cyclopalladated ferrocenylimine complex (Cat. Ⅲ), diaryl ethers were selectively generated by adjusting reaction parameters through the coupling of nitroarenes and arylboronic acids mostly with yields ranging from moderate to good. The reaction only employed1mol%of catalyst loading and the efficiency of this reaction was demonstrated by its compatibility with a range of groups. Additionally, the rigorous exclusion of air or moisture was not required in these transformations and the product is easily separated. This simple methodology provided a efficient pathway for diaryl ethers bearing actives functional groups.