Research On The Minimally Invasive Intracranial Pressure Monitoring Technology And Its Application

Traumatic brain edema is caused with craniocerebral injury. It can lead to high intracranialpressure, brain shift and even life threatening. Because of the disadvantage of large trauma in currentdomestic invasive intracranial pressure detecting technology and the disadvantage of low accuracy innoninvasive intracranial pressure detecting technology, a minimally invasive intracranial pressuremonitoring and drainage device has been designed and developed in this paper, in order to monitorintracranial pressure in the drainage process. Besides, by using minimally invasive near infraredspectroscopy, the relationship between the optimized scattering coefficient and intracranial pressure hasbeen studied, in order to make the optimized scattering coefficient as a cerebral edema evaluation factor.This article is a effective exploration for minimally invasive intracranial pressure monitoringtechnology.The main research contents and results are as follows:(1) An intracranial pressure monitoring anddrainage device has been designed and developed, including an intracranial pressure detection probe, acerebrospinal fluid drainage tube and a pressure testing and displaying device. The calibrationexperiment showed that the device can satisfy the intracranial pressure monitoring requirements, suchas pressure range, stability and accuracy.(2) The intracranial pressure of rats has been detected inreal-time by the device, and comparing with the Codman intracranial pressure monitor, the resultsshowed that the device can accurately detect intracranial pressure of rats.(3) Through the rats edemaexperiments, the results showed that linear relationship between the optimized scattering coefficientand intracranial pressure is good and they can reflect back the changing rule of brain edema after thecraniocerebral trauma and treatment. The optimized scattering coefficient can be used as a brain edemaevaluation factor.The main innovation points are as follows:(1) An intracranial pressure monitoring and drainagedevice has been designed, developed and calibrated, realizing the detection of rats intracranial pressure.(2) Through the rats edema experiments, the mathematical model of the optimized scattering coefficientand intracranial pressure has been established, showing that the ptimized scattering coefficient can beused as a brain edema evaluation factor.