Font Size: a A A

Assessment Effects Of Delayed Percutaneous Coronary Intervention On Left Ventricular Function And Left Ventricular Remodeling In Patients With Acute Myocardial Infarction Using RT-3DE

Posted on:2013-02-11Degree:MasterType:Thesis
Country:ChinaCandidate:Y SunFull Text:PDF
GTID:2234330371478927Subject:Cardiovascular medicine
Abstract/Summary:PDF Full Text Request
Background Acute Myocardial Infarction(AMI) is the most common cause of Congestive Heart Failure(CHF). Its main pathophysiological mechanism is ventricular remodeling. It had been approved by animal experiment and clinical research, that left ventricular remodeling after myocardial infarction can be prevented by reperfusion treatment, thus the ventricular function and prognosis of patients can been improve by it. Percutancous Coronary Intervention(PCI) is one of the effective methods of Coronary Artery Revascularization(CRV). Real-time three-dimensional echocardiography (RT-3DE), as a novel technique, can evaluate architectonic of heart and ventricular function three-dimensionally, accurately, non-invasively, quickly and inexpensively, and not depend on the geometrical assumption of heart. The study will assessment effects of delayed percutaneous coronary intervention on left ventriculafunction and left ventricular remodeling in patients with acute myocardial infarction, to provide reference for clinical cure and prognosis.Objective To assess the effect of delayed percutaneous coronary intervention (PCI) on left ventricular function in patients with acute myocardial infarction by real-time three dimensional echocardiography (RT-3DE).Methods92patients with acute myocardial infarction were enrolled in this study, of those60cases were treated by delayed PCI(PCI group), while32cases recieved medical therapy. All patients underwent RT-3DE before and3months,6months after treatments. Three-dimensional image data were analysed offline to calculate left ventricular end-diastolic volume (LVEDVI), left ventricular end-systolic volume (LVESVI), left ventricular ejection fraction (LVEF), left ventricular mass index(LVMI) and left ventricular remodeling index(LVRI).Results There were no significant difference of LVEDVI, LVESVI, LVEF, LVMI and LVRI between PCI group and medication group before treatments(P>0.05). In PCI group, LVEDVI, LVESVI, LVMI decreased and LVEF, LVRI improved3months after the PCI compared with those before PCI(P<0.05), and the improvement was significant6months after PCI(P<0.01). Compared with medication group, LVEDVI, LVESVI, LVMI was decreased and LVEF, LVRI improved in PCI group(P<0.05). Conclusion Delayed PCI inhibit left ventricular remodeling and improved cardiac function and the prognosis of the patients with acute myocardial infarction. Left ventricular function in patients with acute myocardial infarction can be feasibily and accurately evaluated by RT-3DE.
Keywords/Search Tags:acute myocardial infarction, delayed PCI, real-time three-dimensionalechocardiography, left ventricular function, left ventricular remodeling
PDF Full Text Request
Related items