| Brucellosis, also called Bang’s disease, Crimean fever, Gibraltar fever, Malta fever, Maltesefever, Mediterranean fever, rock fever, or undulant fever, is a highly contagious zoonosis caused byingestion of unsterilized milk or meat from infected animals or close contact with their secretions.Brucellosis induces inconstant fevers, sweating, weakness, anaemia, headaches, depression andmuscular and bodily pain. Brucellosis has been categorized by the Law of the People’s Republic ofChina on Prevention and Treatment of Infectious Diseases as category B infectious disease. It hasspread over more than170countries and regions around the world, and affected28provinces inChina. The duration of the disease can vary from a few weeks to many months or even years. Thedisease will break out repeatedly, and it is hard to be cured completely.Brucellosis is a serious threat to human health and the development of animal husbandry, and itwill disrupt the normal production and life of society. During1930s-1960s, Brucellosis was rampantall over the world, and from1970s to the end of1980s, the world had witnessed a decrease ofBrucellosis. However, since1990s, the disease began to spread again, and after the year of2000, thedeterioration began to accelerate. The trend of Brucellosis in China has basically been the same asthat of the world. Jilin province suffered a lot from brucellosis, its first Brucellosis was discoveredin1938. During the period between July1952and the beginning of1953, due to the rush in ofsheep as commodities, brucellosis became rampant in Jinlin. In the year of1966, Baicheng citybegan to take comprehensive measures to prevent and cure the disease. Therefore, it is urgent forthe Government to pay close attention to the disease and enhance relevant propaganda. Measuressuch as deepening the research of Brucellosis, raising the capability of prevention and treatment andestablishing prevention and control mechanism must be taken immediately.By using relevant materials, this thesis analyzes the situation of brucellosis in Baicheng Citybetween2002and2011. This thesis also analyzes the216cases of brucellosis in the First Hospitalof Jilin University. In order to master the situation of brucellosis in nearly a decade, the atypicalsymptoms and physical traits of these patients were closely observed. The effects of prevent and clinical measures, the accuracy of diagnostics were also evaluated in this paper. This will contributeto the better diagnostic and treatment of brucellosis.This thesis discovered that Taonan County suffered most from brucellosis, Da’an county,Tongyu County, and Taobei County follows, while Zhenlai has the lowest outbreak of brucellosis.In the past ten years, brucellosis kept a rising trend. Although there were fluctuations in the year of2004,2006,2010and2011, the disease has been very much alive all the time. Brucellosis is veryactive in the period between March and August, while it remains relatively stable in the periodbetween October and January. The research also indicated that male patients aged from20to64aremore than female patients at the same age. And inconstant fevers, sweating, weakness, anaemia,headaches, depression and muscular and bodily pain are main symptoms of Brucellosis. Fever,arthralgia and erythra appear more in acute Brucellosis than in sub-acute and chronical Brucellosis.However, sweating and weakness were almost the same during different phases. Lymphadenectasisand hepatosplenomegaly traits were apparent, and they were almost the same during differentphases. Simple Lymphadenectasis happens more than simple hepatosplenomegaly. Changes ofhemogram, blood sedimentation and C-reactive protein happened, but they showed no clear traits;Liver function damage focused on the observable change of alanine aminopherase and AST, but thelevel of serum total bilirubin and x-protein almost kept unchanged; the rate of active hemoculturewas high, but acute phase active rate was relative low than that of sub-acute and chronical phase.The research results in this thesis are helpful to the clinical epidemic disease research ofBrucellosis. It will promote the knowledge level of professional personnel, lower the rate ofmisdiagnose about Brucellosis, and enhance the clinical treatment measures. This research will alsoprovide scientific data support for other relevant researches. |