The Association Between The Blood Stasis Score Of Tradition Chinese Medicine And TIMI Risk Stratification On Patients With Unstable Angina Pectoris

ObjectiveTo study the relation between TIMI risk stratification and Blood stasis score in patients with unstable angina pectoris(UAP), and analyze the relation of blood stasis score and UAP clinical outcomes.MethodsTotal of114patients with UAP was enrolled from March2011to May2011. The demographic data, risk factors, TCM symptoms, syndrome, coronary artery angiography results, relevant physical and chemical examination of the patients, TIMI risk score and Blood stasis score were collected, respectively.ResultsIn March2011to May2011, there are114patients with UAP had been into explore. The Blood stasis score of three branch group was Significantly higher than two branch group(14.22+5.58and12.26+6.06, P<0.05), and the Blood stasis score of three branch group was Significantly higher than one branch group (14.22+5.58and12.75+4.51, P<0.05). The Blood stasis score wasn’t statistical differences between the one branch group and two branch group (12.75and12.26+6.06, P>0.05). In different TIMI risk groups, the Blood stasis score of high risk group was Significantly higher than lower risk group (13.96+5.22and11.50+5.11, P<0.01), and the Blood stasis score of high risk group was Significantly higher than medium risk group (13.96+5.22and11.74+5.14, P<0.01). So that the Blood stasis score increased with TIMI risk stratifications’rise. In different degree of blood stasis syndrome groups, the TIMI risk score of moderate blood stasis group is higher than the mild blood stasis group (4.51+1.03and4.09+0.97, P<0.05); the TIMI risk score of Severe blood stasis group is higher than the moderate blood stasis group (4.88±0.83and4.51±1.03, P<0.05), and significantly higher than the mild blood stasis group (4.88+0.83and4.09+-0.97, P<0.01). Suggest that as the TIMI score of UAP increase with degree of blood stasis aggravating. The Blood stasis score is positive correlation to the change (Raise or lower>0.05mV) of ST and>=3coronary heart disease risk factors (P<0.05), and that is significant positive correlation with the age≧65years old (P<0.01). According to the correlation analysis of Pearson, the Blood stasis score and TIMI risk score of the114patients with UAP is positive correlation (r=0.230, P<0.05), the Blood stasis score and Gensini score was significant positive correlation (r=0.78, P<0.05). So that the Blood stasis score increased with TIMI risk score’s rise.ConclusionThe blood stasis score was positively correlated with Gensini score. The more compromised coronary arteries was associated with the higher blood stasis score, With the augment of TIMI risk score, the blood stasis score of UAP patients was increased correspondly, These results indicated that the blood stasis score could be taken as a qantified index to evaluate the severity of UAP patients in acute phase.