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The Value Of BAEP And SEP For Predictin Of Prognosis In Severe Bain Injury Patients

Posted on:2013-06-04Degree:MasterType:Thesis
Country:ChinaCandidate:Y WuFull Text:PDF
GTID:2234330374484230Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective To explore and analyze nervous system evoked potential in brainstemauditory evoked potential (BAEP) and somatosensory evoked potentials (SEP) inpatients with severe traumatic brain injury (SBI) and prognosis evaluation.Methods Applied evoked potential severe traumatic brain injury patients admittedwithin24hours the line of BAEP, SEP early detection of7-12days of duplicatedetection, by screening the55cases met the study requirements in patients with severetraumatic brain injury, and head CT on admission GCS (Glasgow coma Scale) score of3-8points, measured in24hours knowledgeable of BAEP (brainstem auditory evokedpotentials) and SEP (somatosensory evoked potentials).BAEP examination: reference electrode A1, A2, ground electrode FP2, recordingelectrodes, the CZ. SEP examination: reference electrode CL and FP2, the recordingelectrode the CL ’and C3’, C4,’the ground electrode to the forearm. Brainstem auditoryevoked potential (BAEP) intends to analyze the I, III, IV wave latencies, interpeakintervals, volatility and bilateral volatility difference, somatosensory evoked potentials(SEP) intends to N20wave-based analysis, after injury in2and a half months proposedGOS score, set the GOS score: Ⅰ~II level as a poor prognosis, III~Ⅴ grade for agood prognosis. BAEP and SEP to detect the wave is abnormal assessment indicators:performance of BAEP anomalies for each wave after wave I latency (PL) to extend toextend the peak latency (IPL), or poor waveform differentiation. SEP performance isabnormal cortical potential, the N20wave is missing, PL extend the amplitudedecreased, the waveform of poorly differentiated or poor. Divided the first time andrepeat monitoring results of BAEP, SEP detection into four groups and, give acomprehensive analysis. Results Results are divided into four groups for the first time,55cases of severetraumatic brain injury patients BAEP and SEP detection of BAEP and SEP werenormal in group A, BAEP normal, the SEP abnormalities (group B); of BAEPabnormalities, the SEP is normal for the group C; of BAEP and SEP were abnormal ingroup D; repeated measurements in50patients, BAEP and SEP test results of BAEPand SEP were normal for the A ’group, BAEP normal, SEP abnormal B’ group; ofBAEP abnormalities, the SEP is normal for the C ’group; of BAEP and SEP wereabnormal D ’group. Detect BAEP sensitivity for the first time, and accuracy were77.5%,73%; SEP sensitivity, accuracy was58.0%,64.5%. BAEP sensitivity of repeatdetection, and accuracy were79.3%,70.0%; SEP sensitivity, accuracy was59.0%,66.0%;2and a half months follow-up GOS score level to determine:8cases for thefirst time patients in group A (15%), the prognosis is good in6cases (75%), poorprognosis,2cases (25%); seven cases of group B patients (13%), the prognosis is goodin4cases (57%),3cases with poor prognosis (43%); group C patients,8cases (15%),the prognosis is good for two cases (25%), poor prognosis of six cases (75%); group D32patients (59%), the prognosis is good for two cases (6%), poor prognosis30cases(94%); repeated detection of A ’,7cases of patients (12%), good prognosis of six cases(86%), poor prognosis patients (14%); B’ group and8patients (16%), prognosis good2cases (25%), poor prognosis of six cases (75%); C ’group of9patients (18%), theprognosis is good for three cases (33%), poor prognosis of six cases (66%); D’ patients26cases (32%), the prognosis is good (0)0cases of poor prognosis in26cases (100%).According to GOS score2and a half months,2was refused on50cases of severetraumatic brain injury prognosis of patients with follow-up (except for two cases)20cases with good prognosis patients,28cases of poor prognosis patients, which wasfirst detected BAEP and SEP were normal for the A group and duplicate detectionBAEP and SEP were normal of A,’5cases of patients prognosis are still good in thegroup; repeated detection of BAEP and SEP were abnormal for24patients in group Dand repeat testing BAEP and SEP were abnormal of to D,’ group The prognosis is both bad.Conclusion Abnormal BAEP, SEP degree of severe traumatic brain injury prognosisis more closely related to, and the first monitoring and repeated monitoring of BAEPwere bad, the SEP were abnormal in patients with the same prognosis, evokedpotentials can be a more accurate assessment of patients with severe traumatic braininjury the prognosis Therefore, BAEP and SEP and repeat monitoring is the evaluationof the poor prognosis of patients with severe traumatic brain injury.
Keywords/Search Tags:Severe traumatic brain injury, Brainstem Auditory Evoked Potentials, Somatosensory evoked potentials
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