| Background and objective:Irritable bowel syndrome (IBS) is a kind of abdominal discomfort associated with altered bowel habit for the characteristics of the functional bowel disorders, which can eliminate organic disease after checking out. The disease is one of the most common clinical disorders associated with small intestine and colon function. IBS incidence is about5.5%-7.0%in China. IBS can present many symptoms, which decreased the quality of life of patients. Now, its etiology and pathogenesis are still unclear. Modern western medicine treatment is not so certain. Chinese medicine treatment on IBS shows advantage of definite therapeutic effect, low cost, less side effect. Although research about Chinese medicine on IBS is quite a lot, this did not reach consensus. This study observed in the pill and powder of Chinese medicine on IBS by comparison of the scale scores of main symptoms before and after treatment.Methods:The patients diagnosed with cold-heat jumble according to the visiting sequence were randomly divided into the treatment group (25) and control group (25). The treatment group was given Si Ni San powder (9g boiling water wash) and Wu Mei Wan Pill (10g) every morning and evening. The control group was given Pinaverium Bromide (50mg, tid) and Bifidobacterium capsules (2tablets, tid). The course of treatment of the two groups is two weeks. Three courses were arranged. During the treatment, any other medicines were not prescribed. After the first course, symptoms of both groups were observed. Before and after treatment, symptomatic assessment, psychological scale score, comparison of related therapeutic index changes were analyzed.Result:(1) After the treatment, clinical symptoms of both groups were improved significantly (P<0.01), and the scores compared with the before showed significant difference (P<0.01). The treatment group and the control group the same effect; two groups compare difference has no statistics significance (P>0.05).(2) After treatment, Insomnia and psychological scale scores of treatment group was significantly decreased by compared with the before (P<0.01). Compared with before treatment, the control group showed no significant improvement (P>0.05).Conclusion:1.The Si Ni San (powder) and Wu Mei Wan (pill) can significantly improve abdominal pain, diarrhea, and other symptoms of bowel habit of IBS patients, and can eliminate anxiety.2.The combination of pill and powder treatment can easily release the IBS symptoms and take conveniently. The low price and the certain curative effect is reliable. |
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