Feasibility Study Of Different Anesthetic Drugs Composite Propofol In Elderly Patients With Endoscopic Retrograde Cholangio Pancreatography

Objective：To research the effectiveness and safety of different anesthetic drugscomposite Propofol in elderly patients of endoscopic retrograde cholangio pancre-atography （ERCP）.Methods：ninety ASAⅠorⅡpatients aged60-87yr for elective ERCP were randomlydivided into three groups with30patients each， propofol group（group A）,remifentanil combined with propofol group （group B） and Dezocine combined withpropofol group （group C）:those in group A were anesthetized with propofol whilethose in group B were anesthetized with remifentanil and propofol，in group C wereanesthetized with Dezocine and propofol.HR，SBP，DPB,RR，SpO₂were respectivelyrecorded before and after anesthesia induction,start endoscope， Intraoperativeoperation and finish endoscope intraoperation and revival,the maintenance dose ofpropofol to keeping the BIS score nearby55in the operation，adverse effects andawakening time were also be recorded．Results：The patients of all groups were quiet and stable during the operation．Afterinduction，SBP，RR，SpO₂in each group were lower than before induction P<0．01).Comparison among groups,group B and group C,s HR，SBP was obviously lowerthan group A while group B and group C,s RR，SpO₂was obviously Higher thangroup A during the monment of start endoscope Intraoperative operation and finishendoscope（P<0.05）, Betw-een group B and groupC there is no significant differencein HR,SBP,RR, SpO₂(P>0.05，the waking time，the maintenance dose ofpropofol and adverse effects in group B and group C are also obviously less thangroup A （P<0.05）,while there is no difference between group B and group C（P>0.05）.Conclusion：It is safe and available for remifentanil combined propofol and Dezocinecombined with propofol in elderly patients of endoscopic retrograde cholangiopancreatography （ERCP） since both of the two anes-thesia method could maintainHaemodynamics stationary and breathing stable, less adverse effects and easy to revive,which are all effective and safety anesthesia method in elderly patients withendoscopic retro-grade cholangio pancreatography （ERCP）.