Research On Chronic Hepatitis B About TCM Syndrome Features And Distribution Law

Objective: To study on TCM syndrome characteristics of Chronic Hepatitis B anddistribution law, as well as the the relationship between TCM syndrome type,demographic data, virological indicators, and the liver function parameters.Method: Selected the cases that met the inclusion criteria, combined with the fourdiagnostic information to distinguish the basic syndromes of units, designed quantitativetables of the Chronic Hepatitis B symptoms and signs. Applied statistical methods such asfrequency analysis, factor analysis and clustering analysis for data analysis system, andthrough the epidemiological survey, to study the relationship between traditional Chinesemedicine syndrome of chronic hepatitis B, gender, age and other basic and objectiveindicators.Result:(1) Pathological factors for CHB are Damp, spleen-deficiency, Qi stagnation,blood stasis, and heat evil; Cluster analysis results showed that it had mainly fivesyndrome types: the spleen deficiency stomach type, type of pixu moisture resistance, hotand humid, and type the spleen deficiency and blood stasis, kidney Yin deficiency pattern.(2) Survey of372cases of Chronic Hepatitis B patients,the sex ratio difference was notstatistically significant between the5types, the spleen deficiency stomach type had thesmallest age and the shortest disease duration,compared with other groups, the differencewas statistically significance(P<0.05);(3) Between the TCM syndrome types,there was nosignificant difference on the HBV marker (P>0.05); Hot and humid spleen type onHBV-DNA rate was the highest; we found that there were statistic distinguish on ALT, AST,TBIL(P<0.05), concentration to the spleen deficiency of the highest value of damp and hot;Concentration serum of ALB was highest in type of the spleen deficiency stomach, and spleen moisture resistance was significantly lower than other groups.Conclusion: CHB has mainly five syndrome types: the spleen deficiency stomachtype, type of pixu moisture resistance, hot and humid, and type the spleen deficiency andblood stasis, kidney Yin deficiency pattern; Pathological factors for CHB are moistureresistance, spleen-deficiency, and Qi stagnation, blood stasis, heat evil;disease located inthe spleen.About the5syndrome types of Chronic Hepatitis B, the spleen deficiencystomach type has the smallest age, and the shortest duration, so the spleen deficiencystomach type may be the early stages of the progress of CHB; hot and humid spleen are inpatients with higher viral replication and the the highest liver function index.These explainthat maybe the spleen deficiency in damp and hot type is in the active period; Theobjective indicators can be used as the reference basis for differentiation classification.