Study Of The Effect Of Transcutanclus Electrical Acupoint Stimulation To The Patients With Ovarian Poor Response In The Effect Of Pregnancy Outcome

Objective：To investigate the effects and mechanisms of transcutanclus electricalacupoint stimulation (TEAS) changes in serum sex hormone、sinus follicular number、ovary blood flow and the influence of the pregnancy outcome of the patients with ovarianpoor response. Methods:60cases kidney women diagnosed of ovarian low response or badovarian reserves were randomly divided into two groups,30cases in the tested group and30cases in the controlled group. Both groups were offered western medicine artificialcycle; Tested group additionally undergone electro-acupuncture treatment, compared withthe controlled group.Oberved changes in Kidney symptom scores、serum sex hormone、sinus follicular number、ovary blood flow before and after intervention. The patientsundergoing in-vitro-fertilization and embryo transfer (IVF-ET) adoptgonadotropin-releasing hormone antagonist,while the observation group add with TEAS tohCG injecting day,Observed the doses and days of gonadotrophin（Gn), hormone levels，thickness of endometrium on the hCG injecting day.Compared the number of maturedoocytes outcome，the rate of fertilization，high grade oocyte and embryo, cryopreservationof embryo,cycle canceling rate.Results:1. Kidney symptoms were improved in the testedgroup, with obvious decrease of basal FSH of the level after3month’s intervention （P﹤0.05）. Number of antral follicle has been increased significant significantly（P﹤0.05）.2.2. Ovary blood flow index: PI、RI reduce in the tested group (P﹤0.05).3.Level of E2and thickness of endometrium on the hCG injecting day has been significantly improved（P﹤0.05）.4. Sum of women with pregnancy in tested group has been higher than controlledgroup,but without significant difference.5. Compared with the controlled group,the number of retrieved oocytes and cryopreservation of embryo has been higher（P﹤0.05）.Conclusions: The TEAS could modulate the hypothalamus-pituitary-ovary axis of thepatients with ovarian poor response or bad ovarian reserves, improve ovary blood flow andovarian reaction, increase the number of retrieved oocytes so as to improve the pregnancyrate. The research results of the improvement of ovarian function and the pregnancyoutcome of the patients with ovarian poor response or bad ovarian reserve provide thetheory basis and the treatment method.