The Clinical Research Of Lithospermum Mixture Combined With Mifepristone In Treating Tubal Pregnancy

Objective:To the Lithospermum mixture auxiliary mifepristone treatment of tubal pregnancy and the use of mifepristone alone treatment of ectopic pregnancy to come to the conclusions of the shikonin mixture combined with mifepristone treatment of ectopic pregnancy is ectopic pregnancyconservative treatment of clinical research base.Methods:45patients were randomly divided into two groups, of which treatment group25cases, the choice of shikonin mixture combined with mifepristone; control group (20cases), single-use mifepristone. Treatment group on the same day morning one-time cold water delivery service mifepristone150mg, fast water two hours before and after medication. Stable condition three days after taking the measurement of blood HCG, no significant decline or no decline in accordance with the preceding method again taking150mg mifepristone. Plus Chinese herb Lithospermum mixture in determining the death of the embryo and subtraction with the disease, on the1st one, one three times, seven days for a course, a total of two courses. The treatment process monitoring patient HCG values <1000mIU/ml, B ultrasonic monitoring ectopic pregnancy reduced mass to give the local heat of the the Lithospermum mixture of Chinese medicine residue. The control group only by the above method taking mifepristone1or2times. Finally, the two groups overall efficacy of the serum β-HCG decreased the extent of the pelvic mass absorption time, the number of segments of the various stages of hospitalized patients with abdominal pain NRS compared.Results:(1) two sets of efficiency to compare the treatment group was96%,70%in the control group, two groups were significantly different (P<0.05);(2) treatment group after treatment7,14daysserum β-HCG values (unit:mIU/ml) were1034.81±653.81,408.42±602.81,169.25±593.87, control group after treatment were1504.55±691.42,1086.91±843.27,776.58±1024.14, the treatment group and control groupmedication after3,7,14days, serum β-HCG, respectively, There was a significant difference (P<0.05).(3) totally absorb the time of treatment and control groups pelvic mass (unit:days) for24.72±4.61,31.4The±8.19, the two groups compared, a significant difference.(4) The two groups after two courses of treatment, the treatment group25cases,20cases of abdominal pain, control group20cases,11cases of abdominal pain, number of I all stages of the NRS than the control group less.Conclusion:Mifepristone strong anti-progesterone and traditional Chinese medicine Lithospermum mixture used in combination, can quickly kill the embryo, and promote the decline of the serum β-HCG and speed up the ectopic pregnancy reduced mass and reduce the clinical symptoms of abdominal pain isA conservative treatment of ectopic pregnancy.