Study On The Prognostic Factors Of Patients With The Local Invasive Bladder Cancer

Objective:To investigate the prognostic factors of patients with the localmuscle-invasive bladder cancer. Methods: We retrospectively analyzed the clinical andfollow-up data of133patients with the local muscle-invasive bladder cancer,chose15kinds of the possible prognostic factors: gender,age,nationality,smoking,alcohol dringking,coexisting disease, hydronephrosis,tumor size, multifocality,T stage, lymph node staging,pathological type, histological grade,treatments by Kaplan-Meier method and Logranktest.A multivariate analysis was performed in these patients by the Cox proportionalhazard model. Results: follow-up period from4to114months, the overall survivals at1year,3year, and5year were77%,64%,52%.In univaria: te analysis, T stage, lymph nodestaging, hydronephrosis were found as prognosis factors in survival (P＜0.05).Inmultivariate analysis,T stage (RR＝2.001, P＝0.001), lymph node staging (RR＝2.250, P＝0.045), hydronephrosis (RR＝1.954, P＝0.047) were found as prognosis factors insurvival by the Cox proportional hazard model (P＜0.05). Conclusions: hydronephrosis,T stage, lymph node staging were prognosis factors of patients with the localmuscle-invasive bladder cancer in survival.