Discussion On The Relationship Between Risk Factors And Characteristics Of Coronary Artery Lesion In Premature Coronary Heart Disease Patients

Objective:To investigate the risk factors and characteristics of coronary artery lesion in premature coronary heart disease (PCAD) patients. Methods:66patients Confirmed by coronary angiography were divided into two groups. The first group consisted of31PCAD patients and the second,35patients with late-onset coronary heart disease(LCAD). Within each group patients with coronary heart disease characterized by bladder inhibin C (CysC), central aortic pressure (CAP), and lipoprotein a {l,p (a)} were compared using logistic regression analysis to assess the relovance of these risk factors. Resultxs Lp (a) was significantly higher, while CysC was significantly lower in the PCAD patients than those from the LCAD group. Diastolic blood pressure was significantly higher in both the PCAD and LCAD groups compared to the healthy group. The limitations of the single-vessel disease and the eccentric lesion were significantly higher in the PCAD group than the LCAD group. However, the three-vessel disease, the right coronary artery, the circumflex artery, the concentric and the diffuse lesion were all significantly lower in the PCAD patients than those in the LCAD group. Conclusions:Lp (a) is the main risk factor in PCAD patients. PCAD patients are characterized as having mild coronary artery disease, mostly single-vessel disease, and eccentric lesion.