Application Free Mydriatic Fundus Photography For Diabetic Retinopathy Screening And Risk Factors Analysis

Objective Application free dilated fundus photography to detect type2diabetes mellitus(T2DM) patients fundus, to understand the prevalence of diabetic retinopathy(DR), combined with the lifestyle, complications and the detection of related metabolic, analysis of risk factors associated with DR, so as to achieve the purpose of early prevention, early detection, early treatment for DR.Methods According to the1999World Health Organization (WHO) to develop diabetes diagnosis and classification standards, for the period November2010to December2011in the Sichuan Provincial Peoples Hospital Department of Endocrinology, outpatient and inpatient diagnosis and treatment of1674patients with T2DM, to use freemydriatic fundus camera photography prevalence DR, and in accordance with the2002DR international clinical staging, patients were divided into two groups:non-diabetic retinopathy group (NC group) and DR group, the DR group, including non-proliferative diabetic retinopathy and proliferative diabetic retinopathy. Extracted subjects,fasting venous blood glycated hemoglobin, liplids, blood uric acid, renal function; oral glucose tolerance tese, the detection of C-peptide and insulin; collect24hours urine, urine protein excretion in some patients detected; specimens from a random urine check urine protein/creatinine; part of the patients underwent EMG testing. Analysis of these indicators and the relationship between DR fingertips.Result1A study were detected insubjects1674cases, and ultimately incorporated into the data analysis of1263cases met the indusion criteria, the average age (57.75±12.84) years of age, the mean duration (5.93±5.74) years. NDR716patients(56.69%),the DR547patients(43.31%). The women of DR prevalence was48.33%,38.80%of the prevalence of male DR, sick women than in men.2With age, duration, glycosylated hemoglobin, systolic blood pressure, blood uric, acid increased, diabetes mellitus peripheral neuropathy in patients with increased merger drinking patients with a history of increased prevalence of DR increasing trend, and the difference was statistically significant (P<0.05)3With the frasting plasma glucose,2-hour postprandial blood glucose, triglycerides, LDL-C, total cholesterol, diastolic blood pressure, urinary protein and urine protein/creatinine increase, high-density lipoprotein reduced protein, the prevalence of DR increasing trend, but the difference was not statistically significant (P>0.05)4Body mass index, family history of diabetes, the merger history of smoking, fasting C-peptide and insulin resistance no statistically significant difference beween the index and the DR.5By using logistic regression analysis on the factors:age, duration, women, systolic blood pressure, glycosylated hemoglobin, merger DPN independent risk factor for DR.Conclusion This study of DR prevalence was43.31%,48.33%of the women of DR prevalence rate, the male of DR prevalence rate of38.80%. Age, duration, women, diabetes mellitus, peripheral nerve disease, systolic blood pressure, glycosylated hemoglobin diabetic retinopathy, the independent risk factors.