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Relationship Study Of Diastolic Blood Pressure With Clinical Outcome In Acute Complete MCA Occlusion Patients

Posted on:2014-02-13Degree:MasterType:Thesis
Country:ChinaCandidate:Q YanFull Text:PDF
GTID:2234330395497546Subject:Clinical Medicine
Abstract/Summary:PDF Full Text Request
Objectives: To provide new evidence and clue for treatment and prognosisevaluation of acute complete medial cerebral artery occasion (cMCAO) byinquiring the relationship between diastolic blood pressure (DBP) and other riskfactors with clinical outcomes of cMCAO patients.Method:300ischemic stroke patients were collected at the Department ofNeurology, The First Hospital of Jilin University during January2011toNovember2012. Excel was used to summarize data and SPSS17.0was used toanalyze the data. Depending on the difference type of the data, t test, Wilcoxonrank-sum test, Chi-square test, and Fisher’s exact test was introduced andassessed to have significant statistic difference by p<0.05. Single factor andmulti-factor unconditioned logistic regression analysis and linear trend test werealso used.Results:300ischemic stroke patients’ mean age was63.91±7.23years old with164male. cMCAO patients’ mean age was67.72±6.91years old with58males.Research results showed:(1) Age, sex, smoking, obese, atrial fibrillation, andinternal carotid artery occlusion (ICAO) were closely related with cMCAOdevelopment;(2) Smoking, admission DBP, admission blood glucose, andNIHSS were contributed to cMCAO death;(3) Age, admission DBP, admission blood glucose, and NIHSS were closely related to cMCAO’s death;(4)100~109mmHg DBP was related to the lowest death rate of cMCAO; The risk of deathincreased with the increase of admission DBP increase or decrease (p=0.029,p<0.05).Conclusion:(1) Risk factors of acute cMCAO includes age, sex, smoking, obese,atrial fibrillation, and internal carotid artery occlusion (ICAO);(2) cMCAO deathpredictors included smoking, admission DBP, admission blood glucose, andNIHSS;(3) Age, admission DBP, admission blood glucose, and NIHSS were themajor risk factors of cMCAO’s bad prognosis;(4) Patients with admission DBPhigher than109mmHg or lower than100mmHg were at high risk of badprognosis of cMCAO; The risk of death increased with the increase or decreaseof admission DBP.
Keywords/Search Tags:Diastolic blood pressure (DBP), Acute complete medial cerebral arteryoccasion (cMCAO), Risk factor, Clinical outcome
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