Research On Relationship Among Umbilical Cord Blood Flow S/D Value And Fetal Oxygen Deficient As Well As Delivery Mode In GDM Pregnant Women

Objective: To observe umbilical artery S/D value change rule of umbilical arteryS/D value of the gestational diabetes mellitus(GDM) women and non-GDM women,and relationship between umbilical artery S/D value and fetal exhaust oxygen anddelivery mode. Methods: The data of pregnancy37-42weeks of the pregnant womenin Shenyang Women and Infant Hospital from February to September in2012werecollected, who delivered in maternity ward. The pregnant women with GDM andnon-GDM and without any obstetric complications (including gestational diabetes,premature rupture of membrane, placenta previa, scar uterus, placental abruption,oligohydramnios, twins, the fetus anomaly, etc.) were screened to measure umbilicalartery S/D value by color doppler ultrasound. Then the statistical analysis was done,the relationships among gestational weeks, umbilical artery S/D value mean, changeof umbilical artery S/D value and fetal exhaust oxygen, delivery mode were comparedbetween two groups. Results:①the378cases GDM women amounted49.54%, and385cases non-GDM, amounted50.46%. There was not a significant difference in theproportion of cases number in different delivery weeks between GDM and non GDMgroup. Whereas there was a significant difference in the proportion of cases number indifferent delivery weeks in GDM and non GDM group, respectively(P<0.05）.②Theproportion of cases number during different umbilical artery S/D value range in GDMgroup was significant different from that in non GDM group (P<0.05）. There was asignificant difference in the proportion of cases number during different umbilicalartery S/D value range in GDM and non GDM group, respectively (P<0.05）. Themeans of umbilical artery S/D value in GDM group and non-GDM group were2.89±0.076and2.56±0.138, respectively, and there was a significant differencebetween two groups （P<0.05）.③There was not significant difference in incidenceof fetal intrauterine distress between two groups. Different gestation weeks had a linear relationship to the fetal intrauterine distress in GDM group and non-GDMgroup, respectively（P<0.05）. The rate of fetal intrauterine distress during differentumbilical artery S/D value range has a significantly difference between GDM groupand non-GDM group. Different umbilical artery S/D value range had a linearrelationship to the fetal intrauterine distress in GDM group and non-GDM group,respectively. The umbilical artery S/D value range with markedly rising of the rate offetal intrauterine distress in GDM group was0.09less than that in non-GDM group.④There was not significant difference in the rate of cesarean section between GDMgroup and non-GDM group. The different gestation weeks had a linear relationship tothe rate of cesarean section in two groups, respectively. The rate of cesarean sectionduring different umbilical artery S/D value range had a significantly differencebetween GDM group and non-GDM group. The relationship between of differentumbilical artery S/D value range and the rate of cesarean section was linearrelationship in two groups, respectively. The umbilical artery S/D value range withmarkedly rising rate of cesarean section in GDM group was0.20less than that innon-GDM group. Conclusion:①The meanof delivery weeks of GDM pregnantwomen was one week in advance of non-GDM pregnant women.②The total level ofthe umbilical artery blood flow S/D value in GDM pregnant women was higher thanthat in non-GDM pregnant women, especially after gestation week40.③Theincidence of fetal intrauterine distress in GDM pregnant women was more than that innon-GDM pregnant women.④In GDM pregnant women, the incidence of fetalintrauterine distress significantly increased when the umbilical artery S/D value wasover2.55, and was0.09less than that in non-GDM pregnant women.⑤The rate ofcesarean section in GDM pregnant women was higher than that in non-GSM pregnantwomen.⑥InGDM pregnant women, the rate of cesarean section markedly increasedwhen the umbilical artery blood flow S/D value was over2.75, and was0.2less thanthat in non-GDM pregnant women.