Serum Magnesium Level And Type2Diabetes And Diabetic Nephropathy Correlational Study

Objective: To study the relationship with serum magnesium level andtype2diabetes and the diabetic nephropathy.Method: A selection in our endocrinology has clearly diagnosed w-ithtype2diabetes patients sixty name, according to their UAER in24hoursis divided into normal urine protein group(UAER＜30mg/24h), earlydiabetic nephropathy group(UAER＞30-299mg/24h), Cli-nical diabeticnephropathy group（UAER＞300mg/24h）; and with the same period inour hospital medical center medical healthy subje-cts and name as controlgroup. General data collection (including height, weight, course ofdisease, gender, age, etc.) and testi-ng fasting plasma glucose, fastinginsulin、HbAlC、serum magnesium、HOMA-IR；And the test results wereanalyzed statistically。Conclusion:(1)in diabetic nephropathy each period，magnesium levelswere significantly lower, and compared to normal significantly（P＜0.05）(2) In patients with type2diabetes normoalbuminuriaperiod, early diabetic nephropathy and clinical nephropathy peri-od serummagnesium level showed a significantly negative correla-tion withUAER(r=-0.794，P＜0.001).（3）serum magnesium level in T2DMpatients showed a significantly negative correction with gl-ycosylatedhemoglobin, fasting plasma glucose and insulin resistance (P＜0.001，P＜0.05).