Xiaojian Decoction And Good Attached Pill Combined Western Medicine Therapy In Spleen And Stomach Type Cold Peptic Ulcer Clinical Research

Peptic ulcer (peptic ulcer PU) is a common chronic diseases of the digestive system, refers to occur in the gastrointestinal tract and gastric acid related a peptic ulceration of the mucosa lesions and gastric acid, where the contact of the gastrointestinal tract can occur in any part of the stomach and duodenum, but most common, accounting for about98%of the peptic ulcer. The main clinical manifestations were:long-term seizure periodicity, rhythmic upper abdominal pain pain, heartburn, acid reflux, and accompanied by belching, fullness, loss of appetite and other symptoms.Aim:This topic will be the peptic ulcer patients were divided into the observation group and the control group before and after treatment, the clinical symptom improvement, Availability timely activity sites and other indicators of comparative study. The purpose is to patients with clinical, pathological findings and survival quality score, compared with two group therapy in the treatment of spleen deficiency type with peptic ulcer clinical curative effect.Method:The acquisition of China Academy of Chinese Medical Sciences Wangjing Hospital spleen and stomach diseases and Watson hospital meet the inclusion criteria of spleen deficiency type in patients with peptic ulcer. Through the comparison of before and after treatment, the symptoms and pathology of gastrointestinal quality of life score, of64patients with peptic ulcer patients were divided into the observation group, the control group. Observation group was given Decoction oral, oral omeprazole and clarithromycin2times a day,20mg,0.5mg,0.5g, amoxicillin capsules2times a day,2times a day, for2weeks. The control group only received the therapy of traditional Chinese and Western medicine. These two groups were treated for two weeks, and two weeks of drug withdrawal, withdrawal after repeated endoscopy and observe the curative effect. After4months of follow-up, and to investigate patients from hospital after the survival quality score. Finally, compared two groups of patients in clinical efficacy and quality of life differences.Results:1.In groups of64patients with no age, gender and differences in clinical course, with comparable.2. comparison of the clinical curative effect of observation group of42cases, clinical cure in9cases, effective in17cases, effective in10cases, ineffective in6cases, the total effective rate was85.7%; the control group of22cases,5cases were cured,4cases, effective in6cases, ineffective in7cases, the total effective rate was68.2%. The nonparametric test, the two group during the4week observation period after the improvement of the symptoms, the observation group was better than the control group, with significant difference (P<0.05).3.Analysis of curative effect of3TCM symptoms:observation group before treatment in the patients with symptoms of traditional Chinese medicine clinical score was36.9+6.3; after two weeks of treatment and4months after the scores were:24.4+5.6,12.3+3.2. The nonparametric test, the two group during the4week observation period after the improvement of the symptoms, the observation group was better than the control group, with significant difference (P<0.01).4.quality of life score comparison:the observation group patients before treatment, quality of life score of94.4+12.8;1months after treatment and4months survival quality scores were102.5+11.4,101.7+10.9points, compared with those before treatment was significantly increased (P<0.05) and remained stable; the control group patients before treatment quality of life score of93.1+/-8.5points, after treatment for1months and4months respectively GLQI score is99.6+7.45,92.3+8.23points. The observation group lmonths and4months of life quality were higher than those in the control group and in4months to improve the quality of life is more significant.5.safety evaluation:two groups before and after treatment monitoring of blood, urinary, routine, liver function, electrocardiogram, no obvious changes, statistically no significant difference (P>0.05).Conclusion:Traditional Chinese medicine decoction combined with triple therapy in the treatment of spleen deficiency type gastric peptic ulcer of the total efficiency of85.7%, and the life quality of the patients improved obviously. Simple use of triple therapy in the treatment of peptic ulcer in the total efficiency of68.2%, quality of life did not change significantly. The herbal decoction can effectively relieve the clinical symptoms, to prevent or slow down the progression of a lesion, and can improve the life quality of the patients.