| Research purpose:Critically ill patients with pulmonary infection disease are very important and one of the most common infections, high incidence, the mortality is high. With the improvement of resistant bacteria, super bacteria, the emergence of a new generation of antibiotic research difficulties, and the development of new antibiotics and can’t fundamentally solve a problem, use will soon produce resistance, the treatment of lung infection became a very difficult problem, traditional Chinese medicine is gradually to attention. By researching the conventional treatment in combination with Chinese traditional medicine to western medicine "row poison attack, for what the sepsis treatment critically ill patients with pulmonary infection disease clinical observation of the curative effect, and further to study TCM by promoting a row of phlegm to critically ill patients lung infection of the clinical effectiveness intervention treatment, to improve the clinical symptoms and provide better method for the promotion of the party to provide certain scientific basis.Research Method:The data of38cases of December2010-December2011in traditional Chinese medicine academy of sciences in China during the ICU hospital, accord with pulmonary infection (pneumonia) of TCM syndrome differentiation of weak of Qi and Yin, phlegm heat of hospitalized patients with lung card warm, with random grouping antitheses clinical test methods are classified into the western medicine of Chinese medicine for the routine treatment group (treatment group)19cases, western medicine conventional treatment group (control group)19cases, the treatment group:Chinese medicine drafts oneself party (Thomas row poison attack, for what the sepsis) and western medicine conventional treatment group:pure western medicine routine treatment. Treatment for a week (7days), respectively, in the treatment of day1day7days fill in CRF form, record observation monitoring data, after treatment, the treatment group and control group before and after treatment, clinical curative effect of traditional Chinese medicine CPIS score, compared the symptom score, and contrast white blood cells (WBC) counting, neutrophils percentage (N%), c-reactive protein (CRP), blood oxygen partial pressure, blood pressure, chest radiograph carbon dioxide points result and row sputum volume changes before and after treatment. Compared with two groups of curative effect is to have an advantage more, and an objective evaluation of the traditional Chinese medicine to party (Thomas row poison attack, for what the sepsis) to critically ill patients with pulmonary infection disease intervention the clinical efficacy of treatment. Statistical data are used SPSS17.0statistical software, compared with measuring data t test or rank and inspection (variance not neat), more count material with Fisher’s inspection (n<40), with matching t test before and after treatment for samples of the comparison in the group, independent t test sample treatment between the group after comparison. P<0.05statistically significant. P<0.01has statistically significant differences.Research Results:1. After treatment the clinical curative effect of two groups compared, and the effective rate was84.2%in treatment group and control group in the effective rate was66.7%, analysis of the treatment group clinical curative effect is better than control group;2. After treatment are two groups before and after treatment of TCM symptom scores in the group compared to P=0.00(P<0.01), Pto=0.00(P<0.01), there are significant differences, explain treatment group and control group can significantly reduce patients symptom scores of traditional Chinese medicine; The two groups after treating score more,,P=0.023(P<0.05), there is difference between the treatment group, a control group that can improve symptom scores of traditional Chinese medicine;3. After treatment, the two groups CPIS score before and after treatment within the group compared to P=0.00(P<0.01), Pto=0.00(P<0.01), there are significant differences, explain treatment group and control group can be significantly reduced CPIS score patients; Two way after comparison between treatment score, P=0.01(P<0.05), the difference was statistically significant;4. After treatment, the two groups of patients WBC count, CRP, neutrophils percentage, carbon dioxide points pressure, row sputum volume decreased, blood oxygen partial pressure increases, except the WBC count change is no statistical difference between the two groups, and the rest of the treatment group than in control group were;5. Chest radiograph lung inflammation absorption improve results two groups the comparative analysis, F=0.092(P>0.05), there is no difference statistics. But the treatment group efficient obviously is higher than those in the control group, think the treatment group in promoting lung inflammatory absorb is better than control group, but no difference statistics.Conclusion:1. In the western conventional treatment based on traditional Chinese medicine combined with "row poison attack, for what the sepsis treatment in patients of critical pulmonary infection, reduce the severity of the lung infection, can improve the clinical symptoms, and have a good clinical treatment effect.2. For laboratory, although the change of the white treatment group than the control group no significant difference, but neutrophils down trend treatment group than in the control group down significantly, indicating that this party to reduce the WBC count and neutrophils has certain advantages. Just there was no statistically difference.3. The party can reduce the inflammatory reaction of critically ill patients with pulmonary infection disease.4. The party has a good promote sputum eduction effect. |
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