Peach Siwu Decoction On Osteoblast And Osteoclast In Callus Morphological Effect Of Experimental Research

Objective:this experiment choose Taohongsiwu-soup as intervention factors, a microscope SD rats radius open fractures model after disruption callus of cells in the change of ideology, so as to explore the Taohongsiwu-soup in the treatment of fractures of the mechanism and function.Methods:SD rats85only, all male, weight180g-220g, randomly divided into5groups, group G (observation group), Y group (positive control group), K group (blank control group), J group (sham operation group), Z group (normal group), G, Y, K, J group of each group of20, Z group5. G, Y, K group making open fracture model of rats, group G gavage administration with Taohongsiwu-soup, Y gavage administration with Ossotide Tablets solution, K gavage administration with distilled water, J cut out skin muscle group show the radius, then closed step by step. Z group will not do anything. In3d,7d,14d,21d, G, Y, K, J groups were random excessive anesthesia5rats death, put to death after fracture line1cm interception and bone, in10%formalin solution save, conventional take off calcium, paraffin, cut, HE dyeing, and then in a microscope cells form.Results:the Taohongsiwu-soup can significantly increased in early disruption callus proliferation of osteoblasts in so as to promote the fracture healing.Conclusion:1, health SD rats through the improvement of open fractures turn Chaibenfu’s this model method can make rats successfully radial open fractures model;2, Taohongsiwu-soup can Can promote callus osteoblasts in the bone. So as to promote the fracture healing.3, Taohongsiwu-soup can Can promote osteoclast proliferation, promote the absorption of dead bone, speed up the fracture healing...