| Chronic glomerulonephritis, chronic nephritis for short, is a set of cli nical syndrome, hematuria, proteinuria, edema, hypertension with or are not ass ociated with decreased renal function for the clinical manifestations of gl omerular disease. The disease is divided into primary and secondary glomerul onephritis, the object of this study is primary glomerulonephritis. The incid ence of chronic glomerulonephritis in recent years, more and more high, more and more younger,brings to the national and personal economic burden. Chroni c nephritis is a clinical medical intractable diseases,will eventually deve lop into renal failure,patients have to receiving renal replacement therapy. Western medicine for the treatment is symptomatic treatment, and to eliminat e the effect of hematuria and proteinuria is limited,with the hormone and i mmune inhibitors side effects, patient compliance is poor. Traditional Chines e medicine in the treatment of chronic nephritis curative effect significan tly,can effectively improve renal function,reduce proteinuria and hematuria, delaying kidney function decline. The hope that Chinese medicine treatment o f chronic nephritis, has a certain clinical significance.This research mainly divided into two parts,literature review and clini cal research of traditional Chinese medicine (TCM) in the first part mainly discusses the various experts in chronic nephritis clinical experience summ ary. The second part is a professor at Renhe Lv and11th five year plan the state supports three type four cohort study on syndrome differentiation in patients with chronic kidney disease(CKD) safety and effectiveness, the rese arch is the supplementary part. Based on this study of professor Lv and clin ical experience for many years, the treatment of chronic kidney disease(CKD) in kidney tonify deficiency blood fights method(The basic of the formulas: main and raw huangqi each15g,angelical5g,Salvia miltiorrhizal5g, danpil5g,t ortoise plastronl2g,Cherokeerosel5g, Gordoneuryale seed30g, poriacocosl5g,gri folal5g,zexie10g,galisma10g, radixcyathulael5g, euonymus15g) Treatment of60c ases of chronic nephritis, and set up the control group60cases, to take the same general treatment, western medicine treatment for12months, observe th e glomerular filtration rate,24hours urinary protein quantitative,routine urine urine red blood cells and urine routine urine protein and TCM syndrom e integral to improve the situation. Of the observed data by SPSS17.0data p rocessing.Results showed:1.After treatment compared with the group, glomerular fil tration rate overall exposure group gradually rise, the differences were sta tistically significant (P<0.001),and at12months after treatment had signif icant difference statistically significance (P=0.006);Rather than exposed gr oup of glomerular filtration rate in general is on the decline,and there ar e significant difference in the12months after treatment of statistical si gnificance (P=0.002).2. After treatment compared with the group,24hours urin ary protein quantitative exposure group were decreased, and were statistical ly significant(P<0.001), but comparison between treatment group has no stati stical significance(P=0.175); Rather than a24-hour urine protein quantitati ve exposure group were higher,and were statistically significant (P<0.05),bu t the treatment group comparison between has no statistical significance (P=0.056).3.The curative effect analysis:routine urine urine protein exposed a fter treatment group total effective rate were higher than in non exposed g roup,2months exposure group compared with non exposed group, there was no s tatistically significant difference(P=0.637), treatment for6months and12months exposure group compared with non exposed group, the difference was st at istically significant (P<0.05).4. Routine urine urine red blood cell analys is:the curative effect after treatment total effective exposure group were higher than that of non exposed group, the difference was statistically sign ificant (P<0.001).5. After treatment compared with the group,TCM syndrome int egral overall declining gradually exposed group, statistical ly significant (P <0.001).6. Based on the analysis of curative effect:cases total effective tr catment after the exposure group were higher than that of non exposed group, the difference was statistically significant (P<0.001).Conclusion:1. The kidney tonify deficiency blood fights method for the t reatment of chronic glomerular nephritis have curative effect in protecting renal function, and with prolonged treatment, curative effect is more sign if icant.2. Kidney tonify deficiency blood fights method for the treatment of chr onic glomerular nephritis have curative effect,reduce urinary protein,blood while positively correlated with treatment time.3. Kidney tonify deficiency blood fights treatments for patients with ch ronic glomerulonephritis can obviously improve clinical symptoms, improve qu ali ty of life.The kidney tonify deficiency blood fights is safe and effective method to treat chronic glomerulonephrit is, but long-term use, is worth popularizing further research. |
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