Characteristics Of Cognitive Function In Patients With Schizophrenia And Intervention Study

Objective: This study aimed to use RBANSR and SCWT to measure the investigation ofthe cognitive functions of schizophrenic patients and normal controls to study the cognitiveimpairment characteristics of schizophrenia patients. And patients with schizophrenia werevisual-spatial working memory training, in order to explore the significance of the visual spatialworking memory training on cognitive function damage of schizophrenia patients.Methods: In this study, 174 patients with schizophrenia and189 normal controls for thestudy, applied RBANS and SCWT to study, then compare the results of the existence ofdifferences between the patients group with schizophrenia and the normal control group, Used toanalyze the cognitive dysfunction characteristics of the schizophrenia patients.; in all the subjects,recruiting 36 patients in the study Interventions, and in accordance with the order of recruitmentwere randomly assigned to drug and combination groups, the drug group patients only acceptregular medication, the combined group patients accept the conventional drug treatment andvisual - spatial working memory training, applied SPSS18.0 statistical software to doing t test toexplore the effectiveness of visual - spatial working memory training.Result: The characteristics of cognitive impairment in schizophrenia patients: (1)InRBANS score, all thefactor scores of the two groups are different, and the difference wasstatistically significant (P <0.05). In SCWT scores, there are differences in the two groups inaddition to the time of color interference, and the difference was statistically significant (P<0.05). (2)In RBANS score, male patients in the immediate memory, delayed memory and thetotal scale score difference with female patients, and the difference was statistically significant(P <0.05); different cultures differences in language, and the difference was statisticallysignificant (P <0.05); different marital status differences in immediate memory, attention, andthe total scale score, and the difference was statistically significant (P <0.05). In SCWT scores,male patients in the words time, monochrome, double word and two-color time are different withfemale patients, the difference was statistically significant (P <0.05); different cultures intwo-color time and the interference time of the word meaning are different, and the differencewas statistically significant (P <0.05). Intervention results: tow groups in immediate memory,language, delayed memory and the total scale score differences before and after the intervention,after the intervention scored significantly higher than before the intervention.Compare the two groups difference before and after intervention, (1) increased amplitude ofthe combined group in immediate memory and delayed memory score was significantly greaterthan the drug group, and the difference was statistically significant (p <0.05). (2)The word timeand two-color time of the drug group differences before and after treatment, the difference of rest indicators was not significant. The combined group was significant differences in word time,monochrome time, double word, double color time and word meaning interference time beforeand after the intervention. Compare the two groups difference before and after intervention, thedecrease of the joint group in word time, two-color time and word senses interference timesignificantly greater than the drug group, and the difference was statistically significant (p<0.05).Conclusions: (1) The schizophrenia patients have different degrees of cognitive impairment,particularly in attention, verbal memory and executive function. Gender, age, educational leveland marital status are factors affecting cognitive function impairment. (2) Visual-spatial workingmemory training can improve cognitive function in patients with schizophrenia damage.