Acinetobacter Baumannii Infected In ICU And Drug-resistance Analysis

Objective Retrospective analyzed the epidemical change of AcinetobacterBaumannii in ICU during recently4years.Materials and Methods Collected the146clinical data of patients whoseAcinetobacter Baumannii cultivate was positive,from Jan2008to July2011inGeneral hospital of Ningxia medical univisity.Collected a patient’s generalmaterial,laboratory and clinical data,therapy intervention,prognosis,antimicrobial susceptibility test results.Statistical analysis of the influenceof prognosis of patients,and the source of the patients,the source of the strainsand drug-resistance.P<0.05difference have statistical significance.Results146patients got into study.111patients were alive,and35patientswere dead.The mortality of those patients whose infected Acinetobacter Baumanniiis24.00%.The blood infection have the highest mortality(44.4%). Age and APPACHEII score of the death group were a higher than the alive group(P<0.00).The ICUstay of the death group was shorter than the alive group(P<0.00).80.8%of thesepatients had a history of suspected cross infection during ICU stay,compaer withnon-suspected cross infection patients mortality has indifference statisticalsignificance.The drug resistance rate is rising gradually and multidurg-resistence, and the rate of the commonly antibiotices are over60%. Onlythe amikacin and minocycline still sensitive.Conclusion The infection rate of Acinetobacter Baumannii was4.2%inlaminar ICU.The most common infection of Acinetobacter Baumannii in ICU is respiratory system.The patients suffer from Acinetobacter Baumannii bloodinfection get the highest mortality(44.4%).Suspected cross-infection patientsaccounted for80.8%in ICU.Now Acinetobacter Baumannii have drug-resisitant tomost of the commonly antibiotic.Clinicians should chose appropriate antibiotcsdepend on the antimicrobial susceptibiliti test results.Enhancing themonitoring of Acinetobacter Baumannii and preventing the cross infection is thekey to reduce Acinetobacter Baumanniiin fections.