Clinical Research Of Topography-guided Squint Correction By Microscopy For Children Strabismus

Objective：To observe the symptom of ocular surface, corneal thickness, tear filmstability and astigmatism of children strabismus patients after squint correction bymicroscopy guided by corneal topography．Methods：In a prospective randomized sample controlled clinical study．Fortychildren（60eyes） strabismus patients were randomly divided into two groups：traditional limbal conjunctiva incision squint correction by microscopy(group A,n=20,30eyes); corneal topography guiding incision squint correction by microscopy(group B, n=20,30eyes). The vision, the symptom of ocular surface, Ocular SurfaceDisease Index（OSDI），tear film function and topography tests were performed at1day preoperatively、1week and2weeks postoperatively．Results：There were no significant difference for corneal astigmatism and othercorneal topography idex,, the symptom of ocular surface, OSDI and tear film functionwere found between two groups preoperatively(P>0.05). There were statisticallysignificance for symptom eyes, OSDI, break up time（BUT), SchirmerⅠ test (ST),fluorescein staining（FL）and the height of tear meniscus at preoperative comparedwith the postoperative week1in both two groups (P<0.05), whereas no statisticallysignificance at preoperative compared with the postoperative week2in both twogroups (P＞0.05). There were statistically significance for Km and astigmatism atpreoperative compared with the postoperative week1in group A(P<0.05), whereasno statistically significance at preoperative compared with the postoperative week1in group B(P＞0.05). There were no significant difference for Km and cornealastigmatism at preoperative compared with the postoperative week1in both twogroups (P＞0.05). There were statistically significance for ISV、IHA、IVA、IHD atpreoperative compared with the postoperative week1in group A(P<0.05). Whereasthere were no significant difference for ISV、IHA、IVA、IHD at preoperativecompared with the postoperative week1and week2in group B and the postoperativeweek2in group A(P＞0.05). And there were no significant difference for Se3、Se3.5、Se4、Se4.5，Ie3、Ie3.5、Ie4、Ie4.5，Ne3、Ne3.5、Ne4、Ne4.5, and Te3、 Te3.5、Te4、Te4.5at preoperative compared with the postoperative week1and week2in both two groups (P＞0.05).Conclusion：Topography-guided squint correction by microscopy is a more favorablesolution for children strabismus patients, which can correct the corneal astigmatism,stabilize the tear film，mitigate the symptom of ocular surface and therefore improvethe visual quality.