Short Term Aspirin Joint Clopidogrel Treatment TIA The Clinical Curative Effect Of The Observation And Security Research

ObjectiveIschemic stroke accounted for all types of stroke of about85%, and in recent yearsischaemic stroke have clear ascendant trend. Transient ischemic attack (TIA) is consideredto be the first warning signal of cerebral infarction, once appear, it means the risk ofcerebral infarction increased significantly. Untreated TIA about more than one third of thedevelopment for patients with cerebral infarction, the first time in seven days after the firstoccurred within cerebral infarction in the risk of being a victim than10%, and in five yearsa cerebral infarction occurred the risk of being a victim as high as25%-40%, and in thefirst years most accounts for about half of all happened. So positive treatment as soon aspossible is critical, and antiplatelet therapy is the treatment of ischemic stroke one of themost important methods. In numerous antiplatelet drug, epoxy and enzyme inhibitorsaspirin and ADP receptor antagonist clopidogrel is concerned two drugs. This subjectmainly discusses short-term aspirin joint clopidogrel treatment TIA the clinical curativeeffect of the observation and security.MethedsOur hospital randomly selected neurological in-patients of transient ischemic attack(TIA) in100cases, all patients were no acute cerebrovascular disease events history, areruled out midway for other disease death, acute or chronic infection were no disease,cancer,peptic ulcer, hemorrhagic diseases, thrombocytopenia, serious liver and kidneyfunction not congruent disease. Selected patients were randomly divided into two groups,which use aspirin group of50patients (control), aspirin joint clopidogrel group of50cases(treatment group), two groups in gender, age, body mass index, smoking, alcoholconsumption, blood pressure, blood fat and blood sugar levels are the difference was notstatistically significant. The control group give aspirin (bayer company production, tradename: o worship, specification horse spirit department of0.1/piece of)100mg once a day; The treatment group on the basis of the above add with clopidogrel75mg once a day.Watch four weeks of ischemic cerebrovascular event, and cerebral hemorrhage,gastrointestinal bleeding,gums bleeding, skin mucous membrane bleeding and otheradverse events.ResultsThe treatment group within4weeks again hair TIA and worse for cerebral infarctionof cases significantly less than the control group. Two groups of the healing process all didnot see bleeding tendency patients.ConclusionsClinical symptoms of TIA should be as emergency actively handling routine therapyon the basis of aspirin joint clopidogrel dual antiplatelet therapy, curative effect is distinct,adverse reaction is small, can consider to clinical application...