Study Of The Arteria Umbilicalis And The Dynamics Of Arterial Blood Flow In Brain Of Foetus In Late Pregnancy

Research purposes:Explore normal late pregnancy fetal umbilical artery and middle cerebral artery blood flow parameters and the relationship and high-risk pregnancy gestational age when abnormal fetal umbilical artery and middle cerebral artery blood flow spectrum of meaning.Research methods:Select86cases of obstetrics and gynecology hospital late pregnancy high-risk pregnancy pregnant women and86cases of late pregnancy normal pregnant women as observation group and control group, respectively, the object of study, Through regular respectively after the use of color doppler ultrasound of fetal middle cerebral artery, and umbilical arterial blood flow mechanics index of peak systolic velocity (PSV), end-diastolic velocity (EDV), resistance index (RI), pulse index (PI) and systolic/diastolic peak flow speed at the end of the determination of blood flow velocity (S/D). Calculation of resistance index (RI)=(S-D/S, pulsation index (PI)=(S-D)/M, M is the average blood flow velocity. According to the late pregnancy fetal color doppler ultrasonic testing results, late pregnancy fetal normal pregnancy UA, MCA hemodynamic index changes along with the gestational age, hemodynamic parameters analysis of the relationship with gestational age; Late pregnancy fetal normal pregnancy and late pregnancy high-risk pregnancy fetal umbilical artery and middle cerebral artery blood flow mechanics index of diversity; Late pregnancy high.The results of the study: Normal pregnancy late pregnancy fetal umbilical artery, middle cerebral artery PSV and EDV increased gradually with the increase of gestational age, with significant difference (P<0.05), S/D, RI and PI values gradually decreases with the increase of gestational age, with significant difference (P<0.05); Observation group of fetal umbilical artery PI, RI and S/D value are higher than the control group, with significant difference (P<0.01), EDV value is lower than the control group, with significant difference compared with control group (P<0.01), PSV compared with control group not significant (P>0.05); Observation group of fetal middle cerebral artery PI, RI and S/D values were lower than the control group, with significant difference (P<0.01), PSV and late pregnancy normal pregnancy fetal umbilical artery, middle cerebral artery PSV and EDV increased gradually with the increase of gestational age, with significant difference (P<0.05), S/D, RI and PI values gradually decreases with the increase; Observation group of fetal middle cerebral artery PI, RI and S/D values were lower than the control group, with significant difference (P<0.01), PSV and EDV values are higher than the control group, with significant difference (P<0.01); Observation group of neonatal Apgar score>7branch accounts for less than the control group obviously, with significant difference (P<0.005), the observation group of neonatal Apgar score is5to7points, and<4branch obviously than the control group, percentage have the sex difference (P<0.005); Late pregnancy high-risk pregnancy perinatal outcomes are significantly higher than normal late pregnancy fetal incidence of abnormal, with significant difference (P<0.005); Observation group of neonatal body weight significantly lower than the control group, with significant difference (P<0.05); Observation group MCA indicators in a single vascular abnormalities fetus perinatal outcome in patients with an abnormal detection rate the indicators were higher than in UA patients. Research conclusions:Normal pregnancy late pregnancy fetal umbilical artery, middle cerebral artery PSV and EDV increased gradually with the increase of gestational age, S/D, RI and PI values gradually reduce with the increase of gestational age.Umbilical artery and middle cerebral artery blood flow mechanics index can reflect the status of fetal placenta and fetal brain blood circulation.Umbilical artery and middle cerebral artery blood flow mechanics index and color doppler spectrum image anomaly can be regarded as abnormal fetal intrauterine development of reliable evaluation basis, middle cerebral artery blood flow mechanics index of late pregnancy high-risk pregnancy perinatal outcome prediction more accurate.Umbilical artery and middle cerebral artery hemodynamics index detection of fetal dysplasia hemodynamic parameters evaluation accuracy is superior to the single detection, the fetus intrauterine changes and perinatal outcomes have important clinical implications.