Study Of EMR In The Treatment Of Gastrointestinal Mucosa And Submucosal Lesion

Objective:To observe the clinical efficacy of the endoscopic mucosal resection (EMR) for the treatment of gastrointestinal mucosa and submucosal lesion.Methods:This study was conducted in the department of internal medicine of Lincang hospital from December2010to December2012,100patients with EMR treatment indications were collected from the out-patient department and in-patient department, and all patients were suffering from gastrointestinal mucosa and submucosal lesion. According to the therapeutic indications, EMR was applied to lesion resection; all resected specimens were retrieved for pathologic study. After that, to observe the wound healing, and to confirm if there was any residual lesion and recurrence, regular endoscopies were follow-up in the first, third, sixth, twelfth months, respectively. Results:After the treatment of EMR, the100patients successfully recovered from gastrointestinal mucosa and submucosal lesion. Among them,5patients with intraoperative wound minimal hemorrhage were given blood clots enzyme or titanium clamp to stop bleeding, and no postoperative perforation, localized peritonitis and other serious complications occurred. Two patients whose adenoma was as large as4cm, which had polyps recurrence at the resection site after1month. However, after being removed completely with hot biopsy forceps, no more recurrence was found in the following12months. Additionally, there was no recurrence for the remaining cases.Conclusion:With the help of EMR, the lesions of gastrointestinal mucosa and submucosal lesion were efficiently removed, and the complete pathologic diagnosis was also gained. In addition, plenty of advantages can be found in EMR, such as thorough treatment, relatively simple operation, and few complications. Thus the EMR is an effective microinvasive operation, which is worth being widely used in basic hospitals in future.