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CEA In Early Clinical Evaluation Of Efficacy In The Treatment Of Obstructive Ischemic Encephalopathy

Posted on:2014-06-07Degree:MasterType:Thesis
Country:ChinaCandidate:L ZhuFull Text:PDF
GTID:2254330401983278Subject:Clinical medicine
Abstract/Summary:PDF Full Text Request
Objective: Though observe the early postoperative clinical effect of the carotidendarterectomy (carotid endarterectomy, CEA) in the treatment of obstructiveischemic encephalopathy caused by internal carotid artery stenosis, to confirmthe efficacy in the treatment of carotid endarterectomy for that type ofdiseases, in order to find a treatment to improve the quality of life forsymptomatic patients with carotid artery stenosis.Methods: Score based on preoperative ischemia-induced symptoms (dizziness,vertigo, face of needlestick sense, upper limb heaviness) of the20cases hadbeen diagnosed with symptomatic carotid stenosis, count score0-10points0issymptomless, scores gradually increase stand for the severity of injuriesincrease,10is severe symptoms. Record the changes of the neck and middlecerebral artery blood flow peak of preoperative and postoperative10days,3months,6months. Compared these three sections after operation withpreoperative, observe the amelioration of the ischemic symptoms, the neck andmiddle cerebral artery blood flow peak of patients. in order to comprehensiveevaluation the early clinical efficacy of carotid endarterectomy.Results:1) The improvement of clinical symptoms of Patients with carotidstenosis: there are significant differences of the ischemic symptoms (dizziness,vertigo, facial needlestick sense and upper limb heaviness) betweenpreoperative and postoperative10days,3months,6months(P<0.05).2) The improvement of carotid blood flow: The carotid artery systolic peak of patientsbefore the treatment is (206.7±25.8) cm/s;10days after surgery is (110.0±7.5)cm/s;3months after surgery is (96.5±3.8) cm/s;6months after surgery is(89.6±3.3) cm/s, there are significant differences of carotid artery systolic peakbetween preoperative and postoperative10days,3months,6months(P<0.05).3) The improvement of middle cerebral artery blood flow peak: The MCA ofpatients before the treatment is (51.5±9.6) cm/s;10days after surgery is(147.2±16.8) cm/s;3months after surgery is (134.1±12.6) cm/s;6months aftersurgery is (118.1±10.3) cm/s, there are significant differences of MCA betweenpreoperative and postoperative10days,3months,6months(P<0.05).Conclusions:1) CEA can improve brain blood flow significantly and lighten thepreoperative symptoms of the extrac ranial obstructive cerebral ischemia inpatients in6months.2) CEA can improve the blood supply to the brain ofpatients with extracranial obstructive cerebrovascular disease, it is an effectivemethod to prevention and treatment the occurrence of cerebrovascular disorder.3) CEA can effective treatment the symptomatic patients with carotid arterystenosis, and the surgery is safe and effective,it also can achieve the purpose toimprove the symptoms of cerebral ischemia, effectively improve the quality ofpatients’ life. Therefore, Carotid endarterectomy can be effective in treatingpatients with ischemic encephalopathy, the surgery is safe and effective, shouldbe promoted.
Keywords/Search Tags:Carotid endarterectomy, Carotid artery stenosis, Early efficacy
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