CT Study On The Embolized Splenic Tissue Change Process After The Partial Splenic Artery Embolization

Objective：By analyzing CT, our research aims at probing the change process of the patientsembolized spleen tissue with hepersplenism’s partial splenic embolization (PSE) after theoperation. We also probe how this change affects the patients’ rehabilitation.Methods：From April2009to June2013，we collected the complete follow-up data of46patients with portal hypertension, liver cirrhosis caused by hepatitis B, and hypersplensionafter treating with PSE in the affiliated hospital of the Zunyi Medical College. All patients hadcomplete inspection before the operation and were taken a one-time partial splenic arteryembolization. The CT of upper abdomen, routine blood and liver function were measured andthe clinical manifestation were observed after1week,1month,3months，and half a yearrespectively after the operation. The proportion of each patient’s spleen embolism wascalculated according to the volume of spleen embolization area and noembolism areameasured by theCT images in one week after the operation. According to the differentproportion of Embolism, the patients were divided into two different groups. In group A, theembolization percentage is below50%. In group B, the embolization percentage exceeds50%.Based on the analysis of CT images of embolization of splenic tissue in each observationperiod，the change of tissue infarction，tissue liquefaction, and tissue repair were used todescribe the differences of splenic embolization group. The patients’ hospitalized time and themaintaining time after the rising of blood cells were also collected. The observation data wasanalyzed by the SPSS17.0software package.Results：After a week of PSE operation，the percentage of splenic embolization was measureby CT. There are31patients in group A and the emboliaztion proportion is (45.3±4.2)%.Meanwhile, the emboliaztion proportion is (64.2±10.6)%for the15patients in group B.The CT of splenic emolization changes after a week of operation. All of the46patientsshowed infarction.After a month of operation: the part of splenic embolization did not change and there were still12patients with infarction(26.08%),34patients with rehabilitation(73.91%),4patients of infarction with liquefaction (8.69%). After3months of operation,there were8patients of embolism area infarction with liquefaction (17.37%),27patients withpartial repair (58.69%),19patients with complete repair (41.30%). After half a year ofoperation,4patients with complete repair of splenic emblization area (8.69%),4patients ofembolism area infarction with liquefaction (8.69%),42patients with complete repair(91.31%).After a month of operation, the partial repair of the spleen tissue between the group A and thegroup B were compared. The difference between the two groups has statistical significance(P<0.05）.After three months of operation, the degree of partial repair of the spleen tissuewere compared, the difference between the two groups has statistical significance（P<0.05）.After6months, all the patients in group A showed complete rehabilitationwhile4patients in group B did not show complete rehabilitation（26.66%）.In group A, thearea of splenic emboliaztion in each operation period didn’t show liquefaction., In group B,there are4patients with liquefaction（26.66%） after1month of operation,8patients withliquefaction（53.33%） after3months of operation and they remain liquefaction after6month(26.66%）. Comparing the hospitalized time of the two groups after PSE operation, thedifference between the two groups has statistical significance（P<0.05）. Comparing themaintaining duration time after the rising of peripheral blood cells, of the difference betweenthe two groups has statistical significance（P<0.05）.Conclusion：After the operation of partial splenic embolization, the image of CT willpresent the process of infarction, infarction with liquefaction, partial repair, completerehabilitation, The process of these changes can also represent the curative effect of the PSEoperation and the recovery process of thepatient’s health recover. When the proportion ofsplenic embolization is less than50%, there is not liquefaction in the CT image. Lowerproportion of splenic embolization will lead to quicker recovery in CT images.