The Effects Of Various Of Nutritional Support On Recovery Of Liver Function In Patients With Malignant Obstructive Jaundice After PTCD Surgery

Purpose: To discuss the effects of enteral nutrition and parenteralnutrition on patients with malignant obstructive jaundice after PTCD surgery.Methods: The50cases of malignant obstructive jaundice patients which thegastrointestinal digestive function were poor and limited in eating admitted in DalianCentral Hospital in2009-2012years. These patients were randomly divided into twogroups after PTCD surgery, and one group was given Peptison liquid (EN group), whileanother group was given Calvin (PN group). The different nutrition were continuouslyimplemented11days or more, meanwhile given clinical nutrition therapy. Bloodsample was collected before PTCD and nutritional support therapy after3d,5d,7d and11d, and was analyzed by instrument. The test index included alanine aminotransferase(ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), glutamyltranspeptidase (GGT), total bilirubin (TB IL), direct bilirubin (DB IL) and total bile acid(TBA), albumin (ALB), pre-albumin (PA). Quantitative data was expressed by mean±standard deviation and were analyzed by SPSS11.5statistical software.Result: ALT: Compared with the pre-operation, ALT of both EN group and PNgroup declined obviously, ALT of EN group declined even sharper, the results in7dand11d showed statistical significance, P<0.05. AST: Compared with the pre-operation,AST of both EN group and PN group declined obviously, AST of EN group declinedeven sharper, the results in7d and11d showed statistical significance, P<0.05.GGT:Compared with the preoperational data, the post-operational GGT of both the EN andPN group decline obviously, the GGT of the EN group declines even sharper.Compared with the PN group, the data of the7th day and11th day have statisticallysignificance, P<0.05. ALP: Compared with the preoperational data, the post-operational ALP of both the EN and PN group declined obviously, the ALP of the EN groupdeclined even sharper. Compared with the PN group, the data of the3rd and5th afterthe PTCD have statistical importance, P<0.05. TBIL: Compared with thepreoperational data, the post-operational TBIL of both the EN and PN group declineobviously, the TBIL of the EN group declines even sharper. Compared with the PNgroup, the data of the3rd and11th day have significant difference (P<0.01). However,the data of the5th and7th have even greater significant difference (P<0.001), thus theresult has more statistical importance. DBIL: Compared with the preoperational data,the post-operational DBIL of both the EN and PN group decline obviously, the DBIL ofthe EN group declines even sharper. Compared with the PN group, the data of the7thand11th after the PTCD have statistical importance, P<0.01. TBA: Compared with thepreoperational data, the post-operational TBA of both the EN and PN group declineobviously, the TBA of the EN group declines even sharper. Compared with the PNgroup, the data of the3rd and11th after the PTCD have statistical importance, P<0.05.ALB: Compared with pre-operational data, ALB increased significantly in the11thafter PTCD in both treatment group, while ALB increased more obviously in EN groupthan PN, P<0.05. PA: Compared with pre-operational data, PA increased significantlyin the11th after PTCD in both treatment group, while PA increased more obviously inEN group than PN, P<0.05.Conclusion: The patients with malignant obstructive jaundice after PTCDcan obtain more benefits by inenteral nutrition than the parenteral nutrition, andthe recovery of the liver function is quicker.