Clinical Analysis Of66Cases Of Intraductal Papilloma

Objective: To understand clinical features of breast intraductal papilloma,summarize clinical diagnosis and treatment points of intraductal papilloma.Methods:66cases of patients with breast intraductal papilloma which wereconfirmed by operation and pathology in our hospital from January2011to December2012were collected to analyzed retrospectively the positiverate of Nipple DischargeExfoliative Cytology in breast intraductal papilloma,the imaging features andclassification of lesions ducts in galactography and the coincidence rate with thepathological results.To summarize surgical treatment points and notes.Results:1.The group of66patients were all female, aging from21~84years old.Theaverage age was47.4years old. There were50patients with nipple discharge as themain performance in this group,21patients with nipple discharge did the examinationof Exfoliative Cytology, which was consistent with the pathological diagnosis in9cases, the detection rate was42.9%; Galactography in39cases, which was consistentwith the pathological diagnosis in36cases,the detection rate was92.3%.2.In this group,intraductal papilloma occurred in large ducts in34cases,accounting for94.4%, intraductal papilloma occurred in the middle-small ducts in2cases, accounting for5.6%.The characteristic image of breast intraductal papilloma inGalactography included intraductal filling defects,with ducal expansion toward thenipple,or complete obstruction of major duct,with meniscus like appearance,or theductal with worm-eaten like appearance.3.Color Doppler ultrasound examination was performed in62cases, which wasconsistent with the pathological diagnosis in38cases,the detection rate was61.3%.4.The group of50patients with nipple discharge as the first symptom underwentoperative with intraoperative methylene blue staining lesions ducts+breastcorresponding segment resection,16cases with breast mass as the initial symptom in patients with breast tumor resection. Rapid intraoperative pathological examination andpostoperative pathological examination confirmed that66cases were breast intraductalpapilloma (34cases of solitary intraductal papilloma,18cases of intraductal papillomawith cyclomastopathy,6cases of Intraductal papilloma with Atypical ductalhyperplasia,8cases of Multiple intraductal papilloma). There were no cancer cases inthis group.Postoperative breast appearance did not change significantly in the group of66patients, there was no incision infection, no recurrence of nipple discharge.Patientsrecovered well and was discharged.Conclusion:1.This group of patients,nipple discharge is the most common clinical symptom inpatients with intraductal papillomas (75.8%),followed by breast mass (24.2%),Mean ageof these patients was47.4years old.2.Galactography has a higher coincidence rate in diagnosis of the disease and thepathological results,the coincidence rate in this group is92.3%, it can be used as thefirst choice of the intraductal papilloma.3.Methylene blue staining lesions ducts,as a method of determining the extent ofsurgical resection,is simple,easy,and reliable.4.In view of breast intraductal papilloma with a certain rate of malignanttransformation,patients with breast intraductal papilloma should have surgical treatmentas early as possible after the diagnosis confirmed.