The Impact Of The Escherichia Coli Resistant Line After Colorectal Cancer Patients With Preoperative Oral Intestinal Antibiotics For Bowel Preparation

Objective To explore the impact of the Escherichia coli resistant lineafter colorectal cancer patients with preoperative oral intestinal antibioticsfor bowel preparation。Methods100cases with colorectal cancer were randomly dividedinto observation group and control group. The observation group (50cases)were treated with oral intestinal antibiotics one day. The control group (50cases) were treated with intestinal antibiotics three days. The Colonicmucosa attachments taken from all patients during operation，were bacterialcultured and sensitive testes. The result of2groups was compared.Results The positive rate of colonic mucosa attachments Escherichiacoli culture of One day and the three days were46%and40%；respectively,three days of Escherichia coli than one day group of amikacin, gentamicin,ciprofloxacin and levofloxacin resistance increased (P <0.05); both groupswere all resistant to ampicillin, while ertapenem, imipenem, and PailaWest/tazobactam all sensitive. Conclusion Intestinal antibiotics for colorectal cancer patients withpreoperative bowel preparation, three days program increased resistance forEscherichia coli on the part of the drug, preoperative bowel preparationshould minimize taking antibiotics.