Quantitative Assessment Of Ventricular Function After Transcatheter Closure Of Ventricular Septal Defect By Three-dimensional Echocardiography

Objective:To evaluate the changes of left ventricular function and rightventricular function before and after transcatheter closure of ventricular septaldefect(VSD) using three-dimensional echocardiography(3DE). Then quantitativeanalyzed the changes of left ventricular function and right ventricular function.Methods: The ventricular function of36patients was quantitative assessment3days before TCVSD,1day,1week and1month after TCVSD. The inner diameters ofthe left ventricular end-diastolic diameter (LVEDD) and the right ventricularend-diastolic diameter (RVEDD) were measured by2DE at first, then left ventricularend-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), leftventricular stroke volume (LVSV), left ventricular ejection fraction (LVEF) and rightventricular end-diastolic volume(RVEDV),right ventricular end-systolic volume(RVESV), right ventricular stroke volume (RVSV),right ventricular ejectionfraction(RVEF) were measured by3DE, respectively. And we compared thepreoperative and postoperative indicators of patients.Results: Compared with preoperative figures, the figures of LVEDD,LVEDV,LVESV,LVSV significantly reduced1day after TCVSD(p<0.01). The figuresalso changed obviously1week and1month after TCVSD(p<0.01). But there was noobvious change between1week and1month after TCVSD(p>0.05). As to LVEF, therewere no obvious change1day after TCVSD(p>0.05), but reduced remarkable after1week and1month (P<0.05).RVEDD,RVEDV,RVESV and RVSV significantly reduced1day after TCVSD(p<0.05), compared with preoperative figures. The figures alsochanged obviously1week and one month after TCVSD(p<0.05),there was no obviouschange between1week and1month after TCVSD(p>0.05).There was no obviouschanges of RVEF after TCVSD(p>0.05).Conclusion: Echocardiography plays an important role in the evaluation of cardiac function before and after transcatheter closure. Transcatheter closure of VSDblocks the left to right shunt. In the short period, the left and right ventricular volumesignificantly reduced. And the left ventricular systolic function gradually improved inpostoperative period. However, there was no obvious changes of right ventricularsystolic function.