Effect Of Brain Computer Interface-Based Transcutanclus Electrical Acupoint Stimulation Therapy On Upper Limb Motor Function For Ischemicstroke Patients

Objective:Investigate the efficacy of Brain Computer Interface (BCI) based Transcutanclus Electrical Acupoint Stimulation (TEAS) therapy for ischemicstroke patients with severe upper extremity motor dysfunction and the neurophysiological mechanism.Methods:15ischemicstroke patients were randomly assigned into BCI group (n=8) and control group (n=7). Each patient in two groups received conventional rehabilitation therapies and drug therapy. In addition, patients in BCI group received BCI-based transcutanclus electrical acupoint stimulationtherapy and the stimulative acupoint were Shousanli (LI10) and Waiguan (SJ5).The treatment lasted for8weeks, three times per week and1-1.5hours per time. Patients in control group only received transcutanclus electrical Shousanli (LI10) and Waiguan (SJ5) stimulationtherapy.The treatment lasted for8weeks, three times per week and20minutes per time. The effect of Traditional Chinese Medicine syndrome, Fugl-Meyer Motor Assessment (FMA) of upper extremity and Action Research Arm Test ((ARAT), the online-accuracies and ERD during MI for two groups were evaluated at pre-and post-training.Results:(1) After the treatment, there was no significant difference of the effect of Traditional Chinese Medicine syndrome between two groups (P>0.05).(2)After the treatment, scores of FMA and ARAT for two groups were significantly improve than those of before(P<0.05); scores of FMA and ARATin BCI group were significantly higher than those in control group (P<0.05).(3) After the treatment, the online-accuracies during MI for BCI group were significant higher than those of control group (P<0.05).(4) After the treatment, ERD of affected central brain region for BCI group was enhanced than that of before (P<0.05), meanwhile, ERD of unaffected central brain region for control group was enhanced than that of before (P<0.05), ERD of affected central brain regionfor BCI group significantly enhanced than that of control group (P<0.05).Conclusion:Transcutanclus electrical Shousanli (LI10) and Waiguan (SJ5) stimulationcan improve the motor function of upper extremity for ischemic stroke patients at convalescent stage. Significantly, BCI-based transcutanclus electrical Shousanli (LI10) and Waiguan (SJ5) stimulationcan encourage patients positively engaged in the treatment, making stroke patients’motor function recovery better. It may attribute to that it mayenhance the affected central brain resion activation.