Clinical Observation Of Propofol And Sevoflurane During Anesthesia In Elderly Patients

Objective:clinical observation of propofol and sevoflurane during anesthesia in elderlypatientsMethods:60cases of grade ASA Ⅱ~Ⅲ patients undergo surgery,with34males and26females, aged65to80years of age, body mass48~75kg. All patients undergoingoperation were without lung, brain and endocrine disease, and no history of obesity,liver and kidney disease, no long-term use of mental, neurological history of drug.60cases were randomly divided into two groups, in which a group of sevoflurane andpropofol group are included (group S and P). Carried into the operating room beforeroutine monitoring of heart rate, blood pressure, ECG, pulse oximetry, connectingthe Narcotrend monitoring the relevant indicators of the patient. Open compensatoryexpansion of the outer periphery of the colloid infusion, calculate the amount ofphysical requirements and the cumulative loss surgery continues as the basis forrehydration. After inhaling pure oxygen mask, propofol, fentanyl, midazolam, cis-atracurium are used for rapid induction, the patients reaching conditions are followedby endotracheal intubation.After anesthesia machine control breathing, adjust theparameter values. S group pre-charge: breathing circuit prefilled2.7MAC, inductionand intubation:2.7MAC (4%), anesthesia was maintained:1.3MAC (1.4%), at theend of surgery, close the volatile then adjust the oxygen tank to greater than or equalto5L/min, P composite group are given intravenous infusion of4~6mg· kg-1· h-1propofol, fentanyl before the end of surgery0.5μg· kg-1. Narcotrend30cases in eachgroup in order to maintain the value37-64. Monitoring patients were monitoredduring anesthesia, surgery10min,30min,10min30min before the end of surgery,including: heart rate (HR), blood gas analysis (pH value, O2partial pressure, CO2partial pressure), mean arterial pressure (mean arterial pressure) and observe the postoperative recovery situation.Results:（1）the P and S groups at t2and t3heart rate were compared. P <0.05（2）the P and S groups blood pressure at t2and t3were compared. P <0.05(3) When the oxygen partial pressure is compared to the P and S groups at t2and t3. P <0.05Conclusions:1sevoflurane compared with propofol is easy to obtain a relatively stable heartrate.2sevoflurane compared with propofol is easy to obtain a relatively stable bloodpressure.3Sevoflurane compared to propofol anesthesia can get high oxygen partialpressure during surgery which is benefical to population of lung function decline.