Comparative Study Of High-dose Estrogen Combined Uterine Balloon Stent To Improve The Therapeutic Effect Of Intrauterine Adhesions

objective：Explore the uterine balloon stent combined with high-dose estrogen preventionof intrauterine adhesions and effectiveness of postoperative adhesion formation inpatients with menstrual improve the situation.Methods:A retrospective analysis from November2011to November2013, due to theamount of secondary amenorrhea, or by reducing other reasons in our hospital wasdiagnosed with uterine adhesions and40patients simultaneously intrauterineadhesions decomposition hysteroscopic surgery. Divided into observation group andcontrol group, patients in each group were20cases. The control group received IUDplaced TCRA joint surgery and general treatment dose E2V artificial cycle. TCRAjoint observation group were given uterine balloon and stent surgery IUD placementsurgery and high-dose therapy E2V artificial cycle; compare different treatments forthe prevention of postoperative intrauterine adhesions and efficacy of postoperativeadhesion formation in patients with menstrual improve the situation. Statisticalanalysis was performed using SPSS16.0software, measurement data with x±s,said method χ2test and Spearman correlation analysis to P≤0.05was consideredstatistically significant.Results:1、Comparison of postoperative patients after4-12months of intrauterineadhesions: The study group patients were cured13cases, effective in7cases,0cases,the total effective rate was100%; six cases in the control group were cured, effectivein10cases,4cases, the total effective rate was80%. The two groups, the cure rateand total effective difference was statistically significant (P <0.05). 2、Two groups of patients after1and3months of intrauterine adhesionscompared to the situation: The study group after1month of treatment, adhesions onecase, the total adhesion rate of5%; three months after the adhesions four cases, thetotal adhesion rate of20%, two by comparison, the difference was statisticallysignificant (P <0.05). The control group after a month six cases of adhesion, theadhesion rate of30%overall, three months after the10cases of adhesion, theadhesion rate of50%overall. The difference was statistically significant (P <0.05).1and3months after treatment, the total adhesion rate of the study group and the controlgroup, the difference was statistically significant (P <0.05).3、1,2,3-month postoperative menstrual flow comparison: the study grouptherapy1,2,3months after blood was52.36±7.13ml,50.45±7.85ml,51.40±7.66ml.Control group2and3months after treatment, respectively, by the blood39.26±6.45ml,33.55±7.85ml,36.17±9.63ml. Treatment of the monthly menstrual flowbetween the two groups after, P <0.05, the difference was statistically significant.4、Two groups of patients after artificial cycle stops menstrual flow comparison:two groups of patients before treatment after blood was14.57±12.50ml,11.75±9.68ml; groups of patients stopped therapy of estrogen and progesterone cycle, afterthe blood was40.17±9.32ml,40.05±11.30ml. Were compared between the twogroups before treatment, after the menstrual flow, P <0.05, the difference wasstatistically significant. Volume between the two groups after the treatment periodcompared, P>0.05, the difference was not statistically significant.Conclusion：1、Larger doses of estrogen can stimulate the growth of endometrial acceleration,thus contributing to postoperative endometrial repair, prevent re-occurrence ofadhesions.2、TCRA place after the short-term treatment of uterine balloon stent continueduse of the IUD, form a mechanical inhibition of uterine contractions caused byadhesions, to improve the cure rate of intrauterine adhesions have a significant effect,and can effectively reduce their recurrence of adhesions degree.