QRS Complex And Plasma BNP And Sudden Sardiac Death In Chronic Heart Failure Caused By Correlation Analysis

Objectives:Chronic heart failure (CHF) patients is sudden cardiac death (SCD) in high-risk groups. With insight into the pathophysiology of CHF, clinical symptoms of the CHF patients was significantly improved,significantly prolong life.However, the high incidence of SCD in patients with CHF is still a major challenge to the doctors.In this study,through follow-up study of the relevant medical records,to investigate the correlation between QRS complex and plasma B-type natriuretic peptide levels in patients with CHF incidence of SCD,to better identify high-risk patients,thus giving early intervention.Methods:We continuously recorded318cases of CHF patients from January2011to January2014entered Shandong Tengzhou Central People’s Hospital (180cases of men and women138cases),aged48-82years, mean age63.65±10.74years old.Selected cases must meet American Framing-ham heart failure diagnostic criteria,not less than three months duration,heart function Ⅱ-Ⅳ grade,excluded66cases of non-sinus rhythm, has installed a pacemaker or ICD, complete right bundle branch block and valvular heart disease,After another28patients were lost to follow-up,finally,224patients entered the follow-up of patients with CHF.Medical center also selected200cases of healthy people as a control group. All patients had complete records for age, gender, etiology, the total number of hospital days during follow-up,NYHA classification, LVEF, QRS wave group time, blood biochemistry, drug treatment, etc.And the data were collected and analyzed statistically.Results:1.No statistically significant difference between the CHF patients and the control group in age, gender and body mass index.Common risk factors in patients with CHF include:Hypertension, diabetes etc.The proportion In the CHF group is significantly higher than that in control group,and LVEF、LVEDD、QRS、QTcd、BNP In the CHF group are significantly different from that in control group(P<0.05).2.Endpoint events can be found that the male patients with SCD was significantly higher than the proportion of women(78.12VS21.87).Sudden cardiac death group and non-cardiac sudden death in NYHA group level, LVEF, LVEDD, QRS, QTcd, BNP and ACEI, application of β-blockers were statistically significant (P<0.05).3.QRS complex and plasma BNP levels are closely related to NYHA heart function level. The worse heart function level is, the longer QRS complex is,the higher plasma BNP levels is.4.By multivariate regression analysis:QRS complex correlation with SCD is the largest (OR=5.483), plasma B-type natriuretic peptide levels followed (OR=3.672), LVEF followed (OR=2.596), LVEDD minimum (OR=1.763).5.Joint QRS complex and plasma BNP levels with SCD have a greater correlation (OR=5.562).Conclusion:1.In view of primary hospital conditions, mortality in hospitalized patients with CHF is still very High,3-year follow-average mortality rate of36.61%,9.37%rate of sudden cardiac death, is still at a high level.Male patients with SCD incidence of CHF was significantly higher than females.2.QRS complex and plasma BNP levels are closely related to NYHA heart function level. The worse heart function level is, the longer QRS complex is,the higher plasma BNP levels is.3.QRS complex and plasma BNP levels are closely correlated to the sudden cardiac death rate of patients with CHF.Joint electrocardiogram QRS complex and plasma BNP levels can cause sudden death in patients with CHF to provide early warning in order to better provide for the diagnosis and treatment of patients with CHF and prognosis.