Facilitation And Inhibition In High Obsessive-Compulsive Individual And Obsessive-Compulsive Disorder In NP Task

Obsessive-compulsive disorder is a psychological disorder which is characteristiced with Obsessional thought and compulsive behavior. The patient usually have Pathological doubt、Insert the idea of a constantly、The idea of impulse、 exaggerated evaluate of fear (Obsessional Thoughts) and stiff、repetitive、ritualized behavior (compulsive behavior), Patients with this disorder are not voluntary, and in consequence that are both obsession and anti-obsession as a result of comsming of mental resource and affecting excution of task. Maybe the obsessional thoughts is because of the scarce capacity of OCD patients on Selective attention related materials and Inhibition of irrelevant information materials when they Faced with conflicting information.The Excessive Facilitation on related materials and disinhibition of irrelevant information materials is the key reasons of OCD. Facilitation and Inhibition is the relative twofold of attention. Facilitation refers to Reaction time decrease, Inhibition refers to one’s ability to suppress irrelevant or interfering stimuli. Impairments in inhibition may be measured by an efficiency cost associated with responding to previously inhibited stimulus. Inhibition is an important part of executive function, in a manner of speaking, inhibition is run through all the executive function. OCD patients have further facilitation and fewer inhibition in the negative priming(NP) task,it’s prove the damage of executive function.Negative priming (NP) is defined as the increase in response latency to process a target stimulus in an ignored repetition probe display compared to processing the same stimulus as a target in a control probe display. Positive priming is defined as the decrease in response latency to process a target which is processed before. At present,there are a lot of study Indicate that obsessive-compulsive disorder have fewer inhibition than healthy people.There are a lot of dispute about if there are differences between obsessive-compulsive disorder and healthy people’s Facilitation and Inhibition in different emotional arousal and time interval.This study use negative priming task.The first study separate OCD patients’s facilitation and inhibition on the positive、negative、neutral emotional arousal, discuss if there is significant difference between high obsessive-compulsive individual and low obsessive-compulsive individual.The second study is discuss the characteristic of facilitation and inhibition of high obsessive-compulsive individual and low obsessive-compulsive in different time interval (400ms and1000ms).The last study is discuss the characteristic of facilitation and inhibition of obsessive-compulsive disorder and healthy subjectsin different time interval (400ms and1000ms)The results:(1)The high obsessive-compulsive individual have further facilitation and fewer inhibition in the emotional arousal of negative priming(NP) than low obsessive-compulsive individual.(2) The high obsessive-compulsive individual have further facilitation in the long time interval(1000ms) and fewer inhibition in the short time interval(400ms).(3) The obsessive-compulsive Disorder have further facilitation in the long time interval(1000ms) and fewer inhibition in the short time interval(400ms).