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Recurrence Of ESRS Joint Assessment Of Vascular Ischemic Stroke

Posted on:2014-03-15Degree:MasterType:Thesis
Country:ChinaCandidate:Q ChenFull Text:PDF
GTID:2264330401470716Subject:Internal Medicine
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Objective:1. To evaluate the predictive value of the composite endpointevents for ischemic stroke by Essen Stroke Risk Score.2. To discuss the predictive value of the composite endpoint events forischemic stroke by Essen Stroke Risk Score combining with Color Doppler FlowImaging and intracranial MRA.Methods: This subject performed a retrospective case study, all in-patientswith acute ischemic stroke were selected consecutively from Department ofNeurology, from September2011to March2012.Collected clinical data according tothe description of medical records of all cases. Exclude the cardiogenic ischemicstroke patients. All the rest ischemic stroke patients underwent Essen Stroke RiskScore and ESRS combining with the vascular assessment (Color Doppler FlowImaging and intracranial MRA). we follow-up the composite endpoint events of1year later. evaluate the value that forecast the composite endpoint events of ischemicstroke by combining with Essen Stroke Risk Score and vascular assessment. Allanalyses were performed by the SPSS statistical package version17.0, the tworeceive operating characteristic (ROC) curve was used to assess the predictionaccuracy of the ESRS and ESRS combining with vascular assessment. P<0.05wasconsidered statistically significant.Results: In This subject, a total of252ischemic stroke patients werefollowed up for one-year,38cases of composite endpoint events were happened(15.1%), and214cases were not(84.9%).1.The mean ESRS score in patients who happened composite endpoint events is4.39±1.85,it’s higher than the patients who did not happened composite endpointevents, The comparison was statistically significant(t=-4.481,P=0.000).2.The different score in ESRS combining with vascular assessment, theproportion of the composite end point events increases as the ESRS joint scoreincreases. The diversity was statistically significant(r=0.685, p=0.042). 3. The proportion of composite end point events was higher in patients withESRS≥3,compare with ESRS<3,The diversity was statistically significant(χ~2=4.353,P=0.037).4. The area under the receiver operating characteristic curve was0.696byESRS,(95%CI:0.606-0.787); The area under the receiver operating characteristiccurve was0.745by ESRS combining with vascular assessment (95%CI:0.606-0.787). The results show that both have predictive value in recurrence ofischemic stroke,and the ESRS combining with vascular assessment maybe better.Conclusions:1.The predictive value of the composite endpoint events forischemic stroke by Essen Stroke Risk Score combining with Color Doppler FlowImaging and intracranial MRA maybe better than the ESRS.2. ESRS combining with vascular assessment≥5points,maybe the high-riskpatients.
Keywords/Search Tags:ischemic stroke, composite endpoint events, ESRS, ColorDoppler Flow Imaging, MRA
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