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Correlation Of Hematological Four Indicators And Geographical Environment

Posted on:2014-10-21Degree:MasterType:Thesis
Country:ChinaCandidate:W H ZhouFull Text:PDF
GTID:2264330425453491Subject:Environmental Science
Abstract/Summary:PDF Full Text Request
Hematology is one of the most basic Clinical detection,which has important significance to the determine on human health,therefore, developing a system reference standard is a better way for clinical diagnosis.In this paper, we will predict four indicators reference value of hematology.Platelet is a kind of immune cells,the sugar in the surface can increase the viscosity and form clumps when the blood vessels damaged or broken.At the same time, platelet granule release of the material, further promote coagulation,hemostasis and improve the ability of repairing the damage to blood vessels.But if the number of platelets in the human body increase,there will be a variety of chronic diseases(Such as chronic myeloid leukemia,Polycythemia vera,Essential thrombocythemia and so on.). White blood cells is also a kind of immune cells in the body.In the hospital, the white blood cell count and classification is the most applications in the routine inspection.When the body has disease or inflammation, white blood cells can produce antibodies, swallowe foreign body,resist the invading of pathogens.Serum bilirubin is one of most important in numerous check for liver function.The bilirubin mostly from the hemoglobin which is from old red blood cells rupture and decomposition.The bilirubin is divided into direct bilirubin and indirect bilirubin.The latter is transported to the liver by the circulation of the blood, then come to the direct bilirubin by the action of liver cell enzyme. The increasevivo bilirubin could cause liver disease and liver disease(Hemolytic jaundice,Neonatal jaundice.Incompatible blood transfusion reaction and so on).Plasma viscosity is one of the important factors affecting the blood viscosity,blood lipid and fibrinogen is also an important factor affecting the plasma viscosity. In the clinic,elevation of plasma viscosity will lead to the elevation of blood viscosity.The slow down of the blood flow could cause disease of high cholesterol;The decrease of Plasma viscosity can lead to liver, hypoproteinemia, anemia etc..These indicators in human health occupies an important position, so a set of standard form reference system is particularly important.11indexes will be selected including climate, terrain, soil,elevation, latitude, annual precipitation, soil organic matter, soil bulk density, etc.Quantitative analysis the correlation with platelet (PLT),white blood cell (WBC), serum bilirubin (TBIL) and plasma viscosity (PV) of different age, different gender in healthy Chinese.Although many scholars have studied the correlation of platelets, white blood cell, serum bilirubin, plasma viscosity of local health human with altitude, temperature, humidity correlation.It only on the part of local healthy people whithout carry out the quantitative system research in different areas, different age, different gender health ginseng reference value standard.Like this, a series of research for platelet (PLT), white blood cell (WBC), serum bilirubin (TBIL), plasma viscosity (PV)in healthy people and the geographical factors is the first thing.First of all, the collection of different age, sex, WBC, PLT, TBIL, PV in healthy people is come from manual retrieval all kinds of database and the medical unit in China.Geographical index provided by the center of the State Bureau of Surveying and mapping, the sharing service network of digital China Meteorological, the United Nations Food and Agriculture Organization (FAO) and the system (IIASA),harmonized world soil database,formed by the Study of Vienna international application, and then apply multiple linear regression analysis, principal component analysis, curve fitting simulation method research the relationship between each index and geographical factors.Finally, after testing the paired samples, respectively, select the best simulation equation,Respectively:①The multiple linear regression mode for between healthy adult male platelet reference value and geographical factors: Y=177.382-0.022X1+0.423X7③multiple linear regression model for between healthy adult female platelet reference value and geographical factors: Y=212.790-0.015X1-19.244X11③Curve model for between healthy elderly men white blood cell reference value and geographical factors: Y=e(2.019-427.024/X2)④Curve simulation of between healthy elderly female white blood cell reference value and geographical factors: Y=e(2.040-465.421/X2)⑤Multiple linear regression model for Serum bilirubin between healthy adult male reference value and geographical factors: Y=23.402-0.0800X6⑥Multivariate linear regression model for between healthy adult female reference values of serum bilirubin and geographical factors: Y=18.597-0.002X2-0.00290X8⑦Analysis between healthy adult male plasma viscosity reference value and geographical factors principal component simulation: Y=1.631+0.000175X1+0.0000122X2-0.0000414X3+0.00806X4-0.0141X5-0.000642X6-0.0000947X7+0.000500X8-0.0921X9+0.0164X10+0.00536X11⑧A healthy adult female plasma viscosity analysis between reference value and geographical factors principal component simulation: Y=1.816+0.000137X1+0.0000123X2-0.0000340X3-0.000474X4+0.000343X5-0.00253X6-0.000522X7+0.000347X8-0.0783X9+0.0670X10-0.00209X11Through the above simulation equation,predicting the reference value of the2322county-level and city-level in China,different gender,different age healthy human PLT,WBC,TBIL,PV,Using the Arc Gis to make spatial interpolationon precisely on predictive value,have the tendency distribution map of reference value.
Keywords/Search Tags:hematology, reference value, geographical environment, SPSS softwareanalysis, spatial distribution map
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