Aerobic Fitness Level Regulation On The P50 And P300 Event-related Potentials Of Sensory Gating

Research background: Nowadays with the rapid development of society, human’ssurvival pressure (education, employment, work, housing pressure and so on) isincreasing, which leads to the psychology pressure more and more higher, so peoplesuffering from mental illness and schizophrenia disease are increasing. Attention is akind of ability that the mental activities direct to and focus on something, attentiondeficit is the basis neuropsychological of other cognitive function impairment. P50sensory gating reflects the selective filtering process that the brain filter irrelevantstimuli in the early stage of attention, while P300reflects the attentional resourceswhich the relevant stimulus are distributed by the brain. Both P50and P300belong tothe middle latency components of event-related potentials, and its respectively reflectattention function from different aspects.Research objective：We used cross-sectional survey measures to do further evaluatethe effects of exercise on attention function, and explore the possible mechanism ofexercise to mental health promotion. Evaluated the correlation relationship betweenthe levels of the aerobic fitness and P50sensory gating, cognitive potential P300inyoung college students.Research methods：1Subjects:195different professional subjects were selectedfrom Shandong Normal University. The subjects were selected from an surveyincluded PARQ&YOU questionnaire, people statistical characteristics questionnaire,health condition and medical background questionnaire. Participants reported health,normal hearing, no history of neurological illness, not taking drugs that can affect thefunction of the central nervous system, no bad habits. All the subjects signed theinformed consent before the experiment.2Methods: This study were used theliterature, observation, investigation, experiment, statistics and other research methods.3Research contents:①Compared between the levels of the aerobic fitness and theindexes of P50sensory gating, cognitive potential P300in genders.②Effects of theaerobic fitness levels on the indexes of P50sensory gating and cognitive potentialP300in males.③Effects of the aerobic fitness levels on the indexes of P50sensorygating and cognitive potential P300in females.④The correlation analysis betweenthe levels of the aerobic fitness and the indexes of P50sensory gating, cognitivepotential P300in males.⑤The correlation analysis between the levels of the aerobicfitness and the indexes of P50sensory gating, cognitive potential P300in females.4Test indexes:①The height and weight were measured with RGZ-120-RT instrumentproduced in Wuxi Weighing Apparatus Factory (number:8957).②Blood pressurewas measured with OMRON digital blood pressure monitor which made in OMRONCO.,LTD.③Body composition indexes were tested by Vivente Body CompositionAnalyzer which was made in Korea.④Event-related potentials P50and P300wererecorded by Poseidon NDI-092EMG/evoked Potential Instrument produced inShanghai Haishen Medical Electronic Instrument Factory.⑤Aerobic fitness levelwas tested indirectly by Monark Ergomedic839E biycycle produced in Sweden.5Statistical analysis:Using SPSS15.0for windows to descriptive statistics and inferential statistics.The data were analyzed by correlation analysis and linearregression analysis;difference among groups were analyzed with single factorvariance analysis,independent samples T test.Significant difference was expressed byP<0.05, the very significant difference was expressed by P<0.01,the results wereshowed as X SD.Research results：①The results found that P50sensory gating and event-relatedpotential P300are relatively constant and genders have no significant effects on theimportant indexes of P50and P300(P>0.05).②In males, compared with the low highlevel of aerobic fitness group, the high level of aerobic fitness group’s P50amplitudedifference score S1-S2increased(P=0.064), P50amplitude ratio S2/S1wassignificantly decreased(P<0.01) and P50amplitude formula value100*（1-S2/S1）wassignificantly increased(P<0.01).③In females, compared with the low high level ofaerobic fitness group, the high level of aerobic fitness group’s P50sensory gatingamplitude difference score S1-S2was significantly increased(P<0.05), the P50amplitude ratio S2/S1was significantly decreased(P<0.01) and P50amplitudeformula value100*(1-S2/S1)was significantly increased(P<0.01).④In males,compared with the low high level of aerobic fitness group, the high level of aerobicfitness group’s P300amplitude was significantly increased(P<0.01), P300latency wasdecreased(P=0.058).That is to say the high aerobic fitness levels people can pay moreattention to stimulus and have better cognitive function in males.⑤In females,compared the low high level of aerobic fitness group with the high one, the indexes ofevent-related potential P300were no significant changes (P>0.05).This indicated thataerobic fitness levels had no effects on the event-related potential P300in females.⑥There were significant correlation between P50gating amplitude ratio S2/S1, P50amplitude formula value100*（1-S2/S1） and the level of aerobic fitness inmales(P=0.039<0.05).⑦In females it also existed significant correlation between P50amplitude difference score S1-S2and the level of aerobic fitness(P=0.036<0.05),andhad the very significant correlation between P50amplitude ratio S2/S1, P50amplitude formula value100*（1-S2/S1） and the level of aerobic fitness inmales(P<0.01).Conclusion：Aerobic fitness levels showed different effects on P50and P300whichreflect the attention function in the young people. There is a significant correlationbetween the level of aerobic fitness and P50sensory gating in college students both inmales and in females. The higher level of the aerobic fitness, the better of the P50auditory sensory gating function. This relationship is more obvious in woman students.While the effects of aerobic fitness level on event-related potential P300doesn’t exsitconsistent results between man and woman.Advise:①It suggests that we adopt directly the method of maximum oxygen uptake to do further study on the issue.②And do further research on the effect of aerobic fitness levels on neurobiological mechanisms of P50sensory gating.